Researcher
Peter Vangheluwe
- Disciplines:Physiology, Molecular and cell biology
Affiliations
- Laboratory of Cellular Transport Systems (Division)
Responsible
From1 Oct 2012 → Today - Laboratory of Cellular Transport Systems (Division)
Member
From1 Oct 2007 → Today
Infrastructure
1 - 1 of 1
Projects
1 - 10 of 38
- ATP13A2 agonists for Parkinson’s disease therapyFrom1 Mar 2024 → TodayFunding: IOF - technology validation in lab
- Targeting ATP13A3-dependent Polyamine Transport for Neuroblastoma TherapyFrom3 Jan 2024 → TodayFunding: BOF - doctoral mandates
- Function and regulation of the polyamine transporter ATP13A3 in polyamine homeostasisFrom1 Jan 2024 → TodayFunding: FWO research project (including WEAVE projects)
- Targeting ATP13A3 for neuroblastoma therapyFrom1 Mar 2023 → TodayFunding: IOF - technology validation in lab
- Evaluating polyamines as biomarkers in patients with Parkinson's diseaseFrom1 Mar 2023 → TodayFunding: Foreign private sponsor - undefined
- Investigating the role of ATP13A4 as polyamine transporter in the cellular and in vivo polyamine homeostasisFrom1 Jan 2023 → TodayFunding: FWO research project (including WEAVE projects)
- Polyamine and iron interplay at the interface between mitochondria and lysosomes with its putative implications for Parkinson’s disease.From12 Oct 2022 → TodayFunding: FWO fellowships
- 3D SUper-Resolution to cryo-Electron MIcroscopy to study nanoscale subcellular dynamics and structure that alter in Neurodegenerative Diseases - 3SURE MINDFrom1 May 2022 → TodayFunding: FWO Large scale research infrastructure
- Inter-organelle communication through membrane contact sites in oncology and neurodegenerative diseases (InterAction)From1 Oct 2021 → TodayFunding: Fund Recuperation Fiscal Exemption, BOF - projects
- Dynamic super-resolution microscopy: a gateway for cell biologists to understand molecular machines at work in living cells during homeostasis & diseaseFrom1 Jan 2021 → 31 Dec 2022Funding: BOF - scientific equipment program
Publications
11 - 20 of 93
- The alkalinizing, lysosomotropic agent ML-9 induces a pH-dependent depletion of ER Ca2+ stores in cellulo(2022)
Authors: Martijn Kerkhofs, Peter Vangheluwe, Geert Bultynck, Tim Vervliet
- Inter-organellar Communication in Parkinson's and Alzheimer's Disease: Looking Beyond Endoplasmic Reticulum-Mitochondria Contact Sites(2022)
Authors: Stephanie Vrijsen, Céline Vrancx, Mara Del Vecchio, Johan Swinnen, Patrizia Agostinis, Joris Winderickx, Peter Vangheluwe, Wim Annaert
- Investigation into the pathophysiology of GBA1-associated Parkinson's disease using organelle-specific proteomics(2022)
Authors: Stephanie Vrijsen, Peter Vangheluwe
Pages: S29 - S30 - The lysosome as a master regulator of iron metabolism(2021)
Authors: Francesca Rizzollo, Peter Vangheluwe, Patrizia Agostinis
Pages: 960 - 975 - BNIP3 promotes HIF-1α-driven melanoma growth by curbing intracellular iron homeostasis(2021)
Authors: Matteo Rossi, Chris Van den Haute, Maria Livia Sassano, Abhishek Garg, Francesca Bosisio, Jasper Wouters, Peter Vangheluwe, Wim Annaert, Johan Swinnen, Joost van den Oord, et al.
- The endoplasmic reticulum Ca2+-ATPase SERCA2b is upregulated in activated microglia and its inhibition causes opposite effects on migration and phagocytosis(2021)
Authors: Peter Vangheluwe
Pages: 842 - 857 - ATP13A2 Regulates Cellular α-Synuclein Multimerization, Membrane Association, and Externalization(2021)
Authors: Jianmin Si, Chris Van den Haute, Evy Lobbestael, Sarah van Veen, Peter Vangheluwe, Veerle Baekelandt
- Polyamine Transport Assay Using Reconstituted Yeast Membranes(2021)
Authors: Sarah van Veen, Peter Vangheluwe
- Increased superoxide in GCH1 mutant fibroblasts points to a dopamine-independent toxicity mechanism(2021)
Authors: Dorien Imberechts, Inge Kinnart, Peter Vangheluwe, Wim Vandenberghe
Pages: 10 - 12 - ATP13A3 is a major component of the enigmatic mammalian polyamine transport system(2021)
Authors: Norin Hamouda, Chris Van den Haute, Roeland Vanhoutte, Johan Swinnen, Patrizia Agostinis, Veerle Baekelandt, Wim Annaert, Steven Verhelst, Jan Eggermont, Peter Vangheluwe
Patents
1 - 3 of 3