Researcher
Peter Vangheluwe
- Disciplines:Physiology, Molecular and cell biology
Affiliations
- Laboratory of Cellular Transport Systems (Division)
Responsible
From1 Oct 2012 → Today - Laboratory of Cellular Transport Systems (Division)
Member
From1 Oct 2007 → Today
Infrastructure
1 - 1 of 1
Projects
1 - 10 of 38
- ATP13A2 agonists for Parkinson’s disease therapyFrom1 Mar 2024 → TodayFunding: IOF - technology validation in lab
- Targeting ATP13A3-dependent Polyamine Transport for Neuroblastoma TherapyFrom3 Jan 2024 → TodayFunding: BOF - doctoral mandates
- Function and regulation of the polyamine transporter ATP13A3 in polyamine homeostasisFrom1 Jan 2024 → TodayFunding: FWO research project (including WEAVE projects)
- Targeting ATP13A3 for neuroblastoma therapyFrom1 Mar 2023 → TodayFunding: IOF - technology validation in lab
- Evaluating polyamines as biomarkers in patients with Parkinson's diseaseFrom1 Mar 2023 → TodayFunding: Foreign private sponsor - undefined
- Investigating the role of ATP13A4 as polyamine transporter in the cellular and in vivo polyamine homeostasisFrom1 Jan 2023 → TodayFunding: FWO research project (including WEAVE projects)
- Polyamine and iron interplay at the interface between mitochondria and lysosomes with its putative implications for Parkinson’s disease.From12 Oct 2022 → TodayFunding: FWO fellowships
- 3D SUper-Resolution to cryo-Electron MIcroscopy to study nanoscale subcellular dynamics and structure that alter in Neurodegenerative Diseases - 3SURE MINDFrom1 May 2022 → TodayFunding: FWO Large scale research infrastructure
- Inter-organelle communication through membrane contact sites in oncology and neurodegenerative diseases (InterAction)From1 Oct 2021 → TodayFunding: Fund Recuperation Fiscal Exemption, BOF - projects
- Dynamic super-resolution microscopy: a gateway for cell biologists to understand molecular machines at work in living cells during homeostasis & diseaseFrom1 Jan 2021 → 31 Dec 2022Funding: BOF - scientific equipment program
Publications
41 - 50 of 93
- Store-independent coupling between the Secretory Pathway Ca2+ transport ATPase SPCA1 and Orai1 in Golgi stress and Hailey-Hailey disease(2018)
Authors: Susanne Smaardijk, Jialin Chen, Sara Kerselaers, Thomas Voets, Jan Eggermont, Peter Vangheluwe
Pages: 855 - 862 - Parkinson disease related ATP13A2 evolved early in animal evolution(2018)
Authors: Tine Holemans, Sarah van Veen, Shaun Martin, Norin Hamouda, Jan Eggermont, Peter Vangheluwe
- A Darier disease mutation relieves kinetic constraints imposed by the tail of sarco(endo)plasmic reticulum Ca-ATPase 2b(2018)
Authors: Peter Vangheluwe
Pages: 3880 - 3889 - An autophagy-driven pathway of ATP secretion supports the aggressive phenotype of BRAF(V600E) inhibitor-resistant metastatic melanoma cells (vol 13, pg 1512, 2016)(2018)
Authors: Shaun Martin, Aleksandra M Dudek-Peric, Abhishek D Garg, Heleen Roose, Seyma Demirsoy, Sofie Van Eygen, Freya Mertens, Peter Vangheluwe, Hugo Vankelecom, Patrizia Agostinis
Pages: 1290 - 1290 - Regulation of Ca2+ ATPases by their N- and C-termini(2017)
Authors: Susanne Smaardijk, Peter Vangheluwe, Frank Wuytack
- The P5 Type ATPase Atp13A2, a Parkinson associated gene, coordinates key trafficking mechanisms involved in the maintenance of cancer cell proteostasis(2017)
Authors: Seyma Demirsoy, Patrizia Agostinis, Peter Vangheluwe
- Novel form of complicated hereditary spastic paraplegia (SPG78), due to mutations in the ATP13A2/PARK9 gene(2017)
Authors: Teodora Chamova, Alejandro Estrada-Cuzcano, Shaun Martin, Tine Holemans, Albena Andreeva, Riet Rycke, Dae-In Chang, Sarah van Veen, Jean Samuel, Danny Sorensen, et al.
Pages: 379 - 380 - An autophagy-driven pathway of ATP secretion supports the aggressive phenotype of BRAF(V600E) inhibitor-resistant metastatic melanoma cells(2017)
Authors: Shaun Martin, Abhishek Garg, Heleen Roose, Seyma Demirsoy, Peter Vangheluwe, Hugo Vankelecom, Patrizia Agostinis
Pages: 1512 - 1527 - ATP13A2/PARK9 regulates endo-/lysosomal cargo sorting and proteostasis through a novel PI(3, 5)P2-mediated scaffolding function(2017)
Authors: Seyma Demirsoy, Shaun Martin, sahar Motamedi, Sarah van Veen, Tine Holemans, Chris Van den Haute, Veerle Baekelandt, Peter Vangheluwe, Patrizia Agostinis
Pages: 1656 - 1669 - SPCA2 couples Ca influx via Orai1 to Cauptake into the Golgi/secretory pathway(2017)
Authors: Susanne Smaardijk, Jialin Chen, Frank Wuytack, Peter Vangheluwe
Pages: 141 - 149
Patents
1 - 3 of 3