Researcher
Monique Beullens
- Disciplines:Systems biology
Affiliations
- Laboratory of Biosignaling & Therapeutics (Division)
Member
From1 Oct 2007 → Today - Faculty of Medicine (Faculty)
Member
From1 Oct 2000 → 31 Dec 2002
Projects
1 - 10 of 16
- Chaperone-guided biogenesis and activity regulation of protein phosphatase-1.From1 Jan 2015 → 31 Dec 2018Funding: FWO research project (including WEAVE projects)
- Screening for inhibitors of protein phosphatases that induce mitotic cell death in cancer cellsFrom1 Jan 2015 → 31 Dec 2019Funding: FWO Strategic Basic Research Grant, BOF - Doctoral projects
- Targeting mitotic-exit phosphatases for cancer therapy.From1 Oct 2014 → 30 Sep 2019Funding: BOF - Concerted Research Project from 1994
- Activation of protein phosphatase-1 as a novel cancer therapy.From1 Jan 2013 → 31 Dec 2016Funding: Private funding of national origin - undefined
- Functions of NIPP1 in keratinocyte biology and cutaneous wound repair.From1 Jan 2013 → 31 Dec 2016Funding: FWO research project (including WEAVE projects)
- A MultiMarker Methylation Signature for the diagnosis and prognosis of cancer.From1 Apr 2012 → 31 Mar 2015Funding: IOF - Industrial Research Fund
- Chromatin signaling by protein phosphatase PP1/Repo-Man.From1 Jan 2012 → 31 Dec 2015Funding: FWO research project
- Explorative and therapeutic targeting of protein phosphatase PP1 holoenzymes.From1 Jan 2012 → 31 Dec 2015Funding: FWO research project
- The interactome and function of the PP1γ interactor RepoMan in mitotic spindle assemblyFrom1 Sep 2011 → 17 Dec 2019Funding: BOF - Doctoral projects
- Signaling by protein kinase Melk in multipotent progenitors, astrocytes and malignant astrocytoma.From1 Jan 2010 → 31 Dec 2013Funding: FWO research project
Publications
11 - 20 of 56
- The transcription factor ERG recruits CCR4-NOT to control mRNA decay and mitotic progression(2016)
Authors: Monique Beullens, Mathieu Bollen
Pages: 663 - 672 - Post-translational Control of the Temporal Dynamics of Transcription Factor Activity Regulates Neurogenesis(2016)
Authors: Natalie De Geest, Rob van der Kant, Joost Schymkowitz, Frederic Rousseau, Mathieu Bollen, Monique Beullens, Pierre Vanderhaeghen, Bassem Hassan
Pages: 460 - 475 - Irradiation of necrotic cancer cells, employed for pulsing dendritic cells (DCs), potentiates DC vaccine-induced antitumor immunity against high-grade glioma(2016)
Authors: Lien Vandenberk, Abhishek Garg, Jochen Belmans, Monique Beullens, Patrizia Agostinis, Steven De Vleeschouwer, Stefaan Van Gool
- Cdk1 orders mitotic events through coordination of a chromosome-associated phosphatase switch(2015)
Authors: Junbin Qian, Monique Beullens, Sofie De Munter, Bart Lesage, Mathieu Bollen
Pages: 10215 - The selective inhibition of protein phosphatase-1 results in mitotic catastrophe and impaired tumor growth(2015)
Authors: Claudia Winkler, Sofie De Munter, Nele Van Dessel, Ewald Heroes, Shannah Boens, Monique Beullens, Aleyde Van Eynde, Mathieu Bollen
Pages: 4526 - 37 - Metals in the active site of native protein phosphatase-1(2015)
Authors: Ewald Heroes, Monique Beullens, Luc Van Meervelt, Stefan De Gendt, Mathieu Bollen
Pages: 1 - 5 - MELK-a conserved kinase: functions, signaling, cancer, and controversy(2015)
Authors: Monique Beullens
- Genome-wide promoter binding profiling of protein phosphatase-1 and its major nuclear targeting subunits(2015)
Authors: Toon Verheyen, Janina Goernemann, Iris Verbinnen, Shannah Boens, Monique Beullens, Aleyde Van Eynde, Mathieu Bollen
Pages: 5771 - 5784 - MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cells(2015)
Authors: Shannah Boens, Aleyde Van Eynde, Monique Beullens, Mathieu Bollen
- Inhibitor-3 ensures bipolar mitotic spindle attachment by limiting association of SDS22 with kinetochore-bound protein phosphatase-1(2014)
Authors: Monique Beullens, Mathieu Bollen
Pages: 2704 - 20