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Researcher
Monique Beullens
- Disciplines:Systems biology
Affiliations
- Laboratory of Biosignaling & Therapeutics (Division)
Member
From1 Oct 2007 → Today - Faculty of Medicine (Faculty)
Member
From1 Oct 2000 → 31 Dec 2002
Projects
1 - 10 of 16
- Chaperone-guided biogenesis and activity regulation of protein phosphatase-1.From1 Jan 2015 → 31 Dec 2018Funding: FWO research project (including WEAVE projects)
- Screening for inhibitors of protein phosphatases that induce mitotic cell death in cancer cellsFrom1 Jan 2015 → 31 Dec 2019Funding: FWO Strategic Basic Research Grant, BOF - Doctoral projects
- Targeting mitotic-exit phosphatases for cancer therapy.From1 Oct 2014 → 30 Sep 2019Funding: BOF - Concerted Research Project from 1994
- Activation of protein phosphatase-1 as a novel cancer therapy.From1 Jan 2013 → 31 Dec 2016Funding: Private funding of national origin - undefined
- Functions of NIPP1 in keratinocyte biology and cutaneous wound repair.From1 Jan 2013 → 31 Dec 2016Funding: FWO research project (including WEAVE projects)
- A MultiMarker Methylation Signature for the diagnosis and prognosis of cancer.From1 Apr 2012 → 31 Mar 2015Funding: IOF - Industrial Research Fund
- Chromatin signaling by protein phosphatase PP1/Repo-Man.From1 Jan 2012 → 31 Dec 2015Funding: FWO research project
- Explorative and therapeutic targeting of protein phosphatase PP1 holoenzymes.From1 Jan 2012 → 31 Dec 2015Funding: FWO research project
- The interactome and function of the PP1γ interactor RepoMan in mitotic spindle assemblyFrom1 Sep 2011 → 17 Dec 2019Funding: BOF - Doctoral projects
- Signaling by protein kinase Melk in multipotent progenitors, astrocytes and malignant astrocytoma.From1 Jan 2010 → 31 Dec 2013Funding: FWO research project
Publications
41 - 50 of 56
- Synthesis and characterization of pseudocantharidins, novel phosphatase modulators that promote the inclusion of exon 7 into the survival of motoneuron (SMN) pre-mRNA(2011)
Authors: Mathieu Bollen, Monique Beullens
Pages: 10126 - 10136 - Expression of a Protein Phosphatase 1 Inhibitor, cdNIPP1, Increases CDK9 Threonine 186 Phosphorylation and Inhibits HIV-1 Transcription(2011)
Authors: Aleyde Van Eynde, Monique Beullens, Mathieu Bollen
Pages: 3798 - 3804 - The PP1-R6 protein phosphatase holoenzyme isinvolved in the glucose-induced dephosphorylation and inactivation of AMP-activated protein kinase, a key regulator of insulin secretion, in MIN6 ß cells(2010)
Authors: Monique Beullens, Mathieu Bollen
Pages: 5080 - 91 - The phosphatase interactor NIPP1 regulates the occupancy of the histone methyltransferase EZH2 at Polycomb targets(2010)
Authors: Nele Van Dessel, Lijs Beke, Janina Goernemann, Nikki Minnebo, Monique Beullens, Aleyde Van Eynde, Mathieu Bollen
Pages: 7500 - 12 - The extended PP1 toolkit: designed to create specificity(2010)
Authors: Mathieu Bollen, Monique Beullens
Pages: 450 - 8 - Y65C Missense Mutation in the WW Domain of the Golabi-Ito-Hall Syndrome Protein PQBP1 Affects Its Binding Activity and Deregulates Pre-mRNA Splicing(2010)
Authors: Monique Beullens, Mathieu Bollen
Pages: 19391 - 19401 - Protein Phosphatase 1 Regulates the Histone Code for Long-Term Memory(2009)
Authors: Monique Beullens, Mathieu Bollen
Pages: 13079 - 13089 - Structure and Function of the Two Tandem WW Domains of the Pre-mRNA Splicing Factor FBP21 (Formin-binding Protein 21)(2009)
Authors: Monique Beullens, Emilia Nicolaescu, Bart Lesage, Mathieu Bollen
Pages: 25375 - 25387 - Docking Motif-Guided Mapping of the Interactome of Protein Phosphatase-1(2009)
Authors: Annick Hendrickx, Monique Beullens, Hugo Ceulemans, Aleyde Van Eynde, Emilia Nicolaescu, Bart Lesage, Mathieu Bollen
Pages: 365 - 371 - Nuclear Inhibitor of Protein Phosphatase-1 (NIPP1) Directs Protein Phosphatase-1 (PP1) to Dephosphorylate the U2 Small Nuclear Ribonucleoprotein Particle (snRNP) Component, Spliceosome-associated Protein 155 (Sap155)(2008)
Authors: Monique Beullens, Mathieu Bollen
Pages: 35805 - 35814