Researcher
Monique Beullens
- Disciplines:Systems biology
Affiliations
- Laboratory of Biosignaling & Therapeutics (Division)
Member
From1 Oct 2007 → Today - Faculty of Medicine (Faculty)
Member
From1 Oct 2000 → 31 Dec 2002
Projects
1 - 10 of 16
- Chaperone-guided biogenesis and activity regulation of protein phosphatase-1.From1 Jan 2015 → 31 Dec 2018Funding: FWO research project (including WEAVE projects)
- Screening for inhibitors of protein phosphatases that induce mitotic cell death in cancer cellsFrom1 Jan 2015 → 31 Dec 2019Funding: FWO Strategic Basic Research Grant, BOF - Doctoral projects
- Targeting mitotic-exit phosphatases for cancer therapy.From1 Oct 2014 → 30 Sep 2019Funding: BOF - Concerted Research Project from 1994
- Activation of protein phosphatase-1 as a novel cancer therapy.From1 Jan 2013 → 31 Dec 2016Funding: Private funding of national origin - undefined
- Functions of NIPP1 in keratinocyte biology and cutaneous wound repair.From1 Jan 2013 → 31 Dec 2016Funding: FWO research project (including WEAVE projects)
- A MultiMarker Methylation Signature for the diagnosis and prognosis of cancer.From1 Apr 2012 → 31 Mar 2015Funding: IOF - Industrial Research Fund
- Chromatin signaling by protein phosphatase PP1/Repo-Man.From1 Jan 2012 → 31 Dec 2015Funding: FWO research project
- Explorative and therapeutic targeting of protein phosphatase PP1 holoenzymes.From1 Jan 2012 → 31 Dec 2015Funding: FWO research project
- The interactome and function of the PP1γ interactor RepoMan in mitotic spindle assemblyFrom1 Sep 2011 → 17 Dec 2019Funding: BOF - Doctoral projects
- Signaling by protein kinase Melk in multipotent progenitors, astrocytes and malignant astrocytoma.From1 Jan 2010 → 31 Dec 2013Funding: FWO research project
Publications
1 - 10 of 55
- Towards Dissecting the Mechanism of Protein Phosphatase-1 Inhibition by Its C-Terminal Phosphorylation(2021)
Authors: Rita Derua, Monique Beullens, Mathieu Bollen
Pages: 834 - 838 - Structure-Guided Exploration of SDS22 Interactions with Protein Phosphatase PP1 and the Splicing Factor BCLAF1(2019)
Authors: Mieke Nys, Rita Derua, Monique Beullens, Chris Ulens, Luc Van Meervelt, Mathieu Bollen
Pages: 507 - + - Functions and therapeutic potential of protein phosphatase 1: Insights from mouse genetics.(2019)
Authors: Monique Beullens, Mathieu Bollen, Aleyde Van Eynde
Pages: 16 - 30 - MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cells (vol 35, e00267, 2015)(2018)
Authors: Lijs Beke, Cenk Kig, Joannes TM Linders, Shannah Boens, An Boeckx, Erika van Heerde, Marc Parade, An De Bondt, Ilse Van den Wyngaert, Tarig Bashir, et al.
- A substrate-trapping strategy for protein phosphatase PP1 holoenzymes using hypoactive subunit fusions(2018)
Authors: Dan Wu, Rita Derua, Monique Beullens, Aleyde Van Eynde, Mathieu Bollen
Pages: 15152 - 15162 - Overexpression of PP1-NIPP1 limits the capacity of cells to repair DNA double-strand breaks(2018)
Authors: Dan Wu, Monique Beullens, Aleyde Van Eynde, Mathieu Bollen
- An Attachment-Independent Biochemical Timer of the Spindle Assembly Checkpoint(2017)
Authors: Junbin Qian, Monique Beullens, Maria Giulia Manzione, Lendert Gelens, Mathieu Bollen
Pages: 715 - 730 - The role of RepoMan in chromosome-dependent microtubule nucleation(2017)
Authors: Sofie De Munter, Monique Beullens, Mathieu Bollen
Pages: 181 - 181 - Maternal embryonic leucine zipper kinase (MELK) reduces replication stress in glioblastoma cells (Retraction of Vol 288, Pg 24200, 2013)(2017)
Authors: Cenk Kig, Monique Beullens, Lijs Beke, Aleyde Van Eynde, Johannes T Linders, Dirk Brehmer, Mathieu Bollen
Pages: 12786 - 12786 - Split-BioID: a proximity-biotinylation assay for dimerization-dependent protein interactions(2017)
Authors: Sofie De Munter, Janina Goernemann, Rita Derua, Junbin Qian, Ewald Heroes, Etienne Waelkens, Aleyde Van Eynde, Monique Beullens, Mathieu Bollen
Pages: 415 - 424