Researcher
Kathleen Claes
- Keywords:inherited predisposition for cancer
- Disciplines:Immunogenetics, Clinical genetics and molecular diagnostics, Epigenetics, Genetics, Cancer prevention, Cancer diagnosis, Oncology not elsewhere classified, Molecular diagnostics
Affiliations
- Department of Biomolecular Medicine (Department)
Member
From1 Oct 2018 → Today - Department of Pediatrics and medical genetics (Department)
Member
From1 Mar 1997 → 30 Sep 2018
Infrastructure
1 - 1 of 1
Projects
1 - 10 of 16
- Multi-omics approach to identify pancreatic cancer biomarkers in liquid biopsies of advanced stage patients by pioneering single cell mass spectrometry of CTCs and (epi)genetics characterization of cfDNAFrom1 Oct 2023 → TodayFunding: BOF - projects
- Joint Action on Networks of ExpertiseFrom1 Oct 2022 → TodayFunding: Other EU initiatives out of framework
- Cofunding core facility - UGent NGS CoreFrom1 Jul 2022 → TodayFunding: BOF - research organisations
- In vivo functional evaluation of unclassified variants, found in the breast cancer gene BRCA2, using CRISPR-mediated genome editing in zebrafishFrom15 Nov 2021 → TodayFunding: BOF - doctoral mandates
- Diagnosing HEreditary predisposition syndromes for Childhood cancer: Implementation in clinical PRactice (DHECIPR)From1 Jan 2021 → TodayFunding: FWO Applied Biomedical Research (TBM)
- CONDITIONAL: COvid-19: iNterplay between genetic preDisposITION and immunologicAl LandscapeFrom15 Apr 2020 → 14 Apr 2021Funding: BOF - projects
- Heading towards an in vivo predictive test for personalized ovarian cancer treatment: application of novel therapies in zebrafish patient derived xenograftsFrom1 Nov 2019 → TodayFunding: FWO Strategic Basic Research Grant
- RAPID - Radiosensitivity Analysis for patients with a Primary Immunodeficiency DiseaseFrom1 Oct 2018 → 30 Sep 2022Funding: FWO Applied Biomedical Research (TBM)
- Immunomonitoring of patients with non-small cell lung carcinoma treated with a tumor mutanome-targeted dendritic cell vaccineFrom1 Jan 2018 → 31 Dec 2021Funding: BOF - Doctoral projects
- Pancreatic cancer: hope to improve prognosis through thorough analysis of DNA and RNA markers for diagnosis and therapy monitoring in liquid biopsiesFrom1 Sep 2017 → 31 Dec 2023Funding: Nonprofit institution or equivalents
Publications
41 - 50 of 80
- Analysis of patients with a personal and/or family history of pancreatic cancer with a custom designed broad cancer predisposition gene panel(2019)Volume: 27
Authors: Greet Wieme, Toon Rosseel, Bram Parton, Bettina Blaumeiser, Sabine Tejpar, Bruce Poppe, Kim De Leeneer, Kathleen Claes
Pages: 1593 - 1593 - BRCA1 and BRCA2 5U+2032 noncoding region variants identified in breast cancer patients alter promoter activity and protein binding(2018)
Authors: Leslie J Burke, Jan Sevcik, Gaetana Gambino, Emma Tudini, Eliseos J Mucaki, Ben C Shirley, Phillip Whiley, Michael T Parsons, Kim De Leeneer, Sara Gutiérrez-Enríquez, et al.
Pages: 2025 - 2039 - Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations(2018)
Authors: Timothy R Rebbeck, Tara M Friebel, Eitan Friedman, Ute Hamann, Dezheng Huo, Ava Kwong, Edith Olah, Olufunmilayo I. Olopade, Angela R Solano, Soo-Hwang Teo, et al.
Pages: 593 - 620 - Extreme clustering of type-1 NF1 deletion breakpoints co-locating with G-quadruplex forming sequences(2018)
Authors: Anna Summerer, Victor-Felix Mautner, Meena Upadhyaya, Kathleen Claes, Josef Högel, David N Cooper, Ludwine Messiaen, Hildegard Kehrer-Sawatzki
Pages: 511 - 520 - Association of breast cancer risk in BRCA1 and BRCA2 mutation carriers with genetic variants showing differential allelic expression : identification of a modifier of breast cancer risk at locus 11q22.3(2017)
Authors: Yosr Hamdi, Penny Soucy, Karoline B. Kuchenbaeker, Tomi Pastinen, Arnaud Droit, Audrey Lemacon, Julian Adlard, Kristiina Aittomaki, Irene L. Andrulis, Adalgeir Arason, et al.
Pages: 117 - 134 - An international survey of surveillance schemes for unaffected BRCA1 and BRCA2 mutation carriers(2016)
Authors: Dana Madorsky-Feldman, Miri Sklair-Levy, Tamar Perri, Yael Laitman, Shani Paluch-Shimon, Rita Schmutzler, Kerstin Rhiem, Jenny Lester, Beth Y Karlan, Christian F Singer, et al.
Pages: 319 - 327 - The genetic basis of undiagnosed muscular dystrophies and myopathies: results from 504 patients(2016)
Authors: Marco Savarese, Giuseppina Di Fruscio, Annalaura Torella, Chiara Fiorillo, Francesca Magri, Marina Fanin, Lucia Ruggiero, Giulia Ricci, Guja Astrea, Luigia Passamano, et al.
Pages: 71 - 76 - Inheritance of deleterious mutations at both BRCA1 and BRCA2 in an international sample of 32,295 women(2016)
Authors: Timothy R Rebbeck, Tara M Friebel, Nandita Mitra, Fei Wan, Stephanie Chen, Irene L Andrulis, Paraskevi Apostolou, Norbert Arnold, Banu K Arun, Daniel Barrowdale, et al.
- Candidate genetic modifiers for breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers(2015)
Authors: P Peterlongo, J Chang-Claude, KB Moysich, A Rudolph, RK Schmutzler, J Simard, P Soucy, RA Eeles, DF Easton, U Hamann, et al.
Pages: 308 - 316 - Non coding RNA molecules as potential biomarkers in breast cancer(2015)
Authors: Kim De Leeneer, Kathleen Claes, R Scatena
Pages: 263 - 275