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Project
CONDITIONAL: COvid-19: iNterplay between genetic preDisposITION and immunologicAl Landscape
This prospective, multidisciplinary and multicentric study aims to gain insights into genetic defects, immunological pathways, and expression shifts that may render some individuals more prone to severe COVID-19. Integrated multi-omics analysis will be used to identify critical host genes and
pathways involved in the infectious process and pathophysiological mechanisms in previously healthy young individuals with severe COVID-19.
Date:15 Apr 2020 → 14 Apr 2021
Keywords:Severe COVID-19, inborn errors of immunity, immunophenotypical characteristics
Disciplines:Medical transcriptomics, Innate immunity, Clinical genetics and molecular diagnostics, Genetic predisposition, Immunogenetics