Researcher
Kathleen Claes
- Keywords:inherited predisposition for cancer
- Disciplines:Immunogenetics, Clinical genetics and molecular diagnostics, Epigenetics, Genetics, Cancer prevention, Cancer diagnosis, Oncology not elsewhere classified, Molecular diagnostics
Affiliations
- Department of Biomolecular Medicine (Department)
Member
From1 Oct 2018 → Today - Department of Pediatrics and medical genetics (Department)
Member
From1 Mar 1997 → 30 Sep 2018
Infrastructure
1 - 1 of 1
Projects
1 - 10 of 16
- Multi-omics approach to identify pancreatic cancer biomarkers in liquid biopsies of advanced stage patients by pioneering single cell mass spectrometry of CTCs and (epi)genetics characterization of cfDNAFrom1 Oct 2023 → TodayFunding: BOF - projects
- Joint Action on Networks of ExpertiseFrom1 Oct 2022 → TodayFunding: Other EU initiatives out of framework
- Cofunding core facility - UGent NGS CoreFrom1 Jul 2022 → TodayFunding: BOF - research organisations
- In vivo functional evaluation of unclassified variants, found in the breast cancer gene BRCA2, using CRISPR-mediated genome editing in zebrafishFrom15 Nov 2021 → TodayFunding: BOF - doctoral mandates
- Diagnosing HEreditary predisposition syndromes for Childhood cancer: Implementation in clinical PRactice (DHECIPR)From1 Jan 2021 → TodayFunding: FWO Applied Biomedical Research (TBM)
- CONDITIONAL: COvid-19: iNterplay between genetic preDisposITION and immunologicAl LandscapeFrom15 Apr 2020 → 14 Apr 2021Funding: BOF - projects
- Heading towards an in vivo predictive test for personalized ovarian cancer treatment: application of novel therapies in zebrafish patient derived xenograftsFrom1 Nov 2019 → TodayFunding: FWO Strategic Basic Research Grant
- RAPID - Radiosensitivity Analysis for patients with a Primary Immunodeficiency DiseaseFrom1 Oct 2018 → 30 Sep 2022Funding: FWO Applied Biomedical Research (TBM)
- Immunomonitoring of patients with non-small cell lung carcinoma treated with a tumor mutanome-targeted dendritic cell vaccineFrom1 Jan 2018 → 31 Dec 2021Funding: BOF - Doctoral projects
- Pancreatic cancer: hope to improve prognosis through thorough analysis of DNA and RNA markers for diagnosis and therapy monitoring in liquid biopsiesFrom1 Sep 2017 → 31 Dec 2023Funding: Nonprofit institution or equivalents
Publications
21 - 30 of 80
- Missing heritability in Bloom syndrome : first report of a deep intronic variant leading to pseudo‐exon activation in the BLM gene(2021)
Authors: Lynn Backers, Bram Parton, Marieke De Bruyne, Simon Tavernier, Kris Van Den Bogaert, Bart Lambrecht, Filomeen Haerynck, Kathleen Claes
Pages: 292 - 297 - Timing of blood sampling for butyrylcholinesterase phenotyping in patients with prolonged neuromuscular block after mivacurium or suxamethonium(2021)
Authors: Nesse Mintjens, Roy Brummans, Filiep Soetens, Kathleen Claes, Luc E. Vanlinthout
Pages: 182 - 187 - Somatic mosaics in hereditary tumor predisposition syndromes(2021)
Authors: Verena Steinke-Lange, Robin de Putter, Elke Holinski-Feder, Kathleen Claes
- Shallow whole-genome sequencing of plasma cell-free DNA accurately differentiates small from non-small cell lung carcinoma(2020)
Authors: Lennart Raman, Malaïka Van der Linden, Kim Van der Eecken, Karim Vermaelen, Ingel Demedts, Veerle Surmont, Ulrike Himpe, Franceska Dedeurwaerdere, Liesbeth Ferdinande, Yolande Lievens, et al.
- Isolation and engraftment of circulating tumor cells into zebrafish embryos to predict tumor response of ovarian cancer patients(2020)Volume: 26
Authors: Charlotte Fieuws, Jeroen Vierstraete, Koen Van de Vijver, Hannelore Denys, Kathleen Claes
Pages: 82 - 82 - Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome(2020)
Authors: Vivien Béziat, Simon Tavernier, Yin-Huai Chen, Cindy S. Ma, Marie Materna, Arian Laurence, Jens Staal, Dominik Aschenbrenner, Lisa Roels, Lisa Worley, et al.
- Cancer Risks Associated With Germline PALB2 Pathogenic Variants: An International Study of 524 Families(2020)
Authors: Xin Yang, Goska Leslie, Alicja Doroszuk, Sandra Schneider, Jamie Allen, Brennan Decker, Alison M. Dunning, James Redman, James Scarth, Inga Plaskocinska, et al.
Pages: 674 - 687 - Missing heritability in Bloom syndrome : first report of a deep-intronic variant leading to pseudo-exon activation in the BLM gene(2020)
Authors: Lynn Backers, Bram Parton, Marieke De Bruyne, Simon Tavernier, Kris Van Den Bogaert, Bart Lambrecht, Filomeen Haerynck, Kathleen Claes
Number of pages: 1 - First patient with bloom syndrome caused by a deep intronic variant leading to pseudoexon activation(2020)
Authors: Lynn Backers, Bram Parton, Stephanie Vermeulen, Marieke De Bruyne, Kris Van Den Bogaert, Anne Vral, Ans Baeyens, Simon Tavernier, Filomeen Haerynck, Kathleen Claes
Number of pages: 1 - Twenty years of BRCA1 and BRCA2 molecular analysis at MMCI : current developments for the classification of variants(2019)
Authors: E Machackova, Kathleen Claes, M Mikova, J Hazova, E Stahlova Hrabincova, P Vasickova, M Trbusek, M Navratilova, M Svoboda, L Foretova
Pages: 2S51 - 2S71