Researcher
Jef Rozenski
- Disciplines:Biomarker discovery and evaluation, Drug discovery and development, Medicinal products, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences, Bioinformatics and computational biology
Affiliations
- Medicinal Chemistry (Rega Institute) (Division)
Member
From1 Oct 1999 → Today
Projects
1 - 10 of 12
- Exploration of the pharmacokinetics of clindamycin and its metabolites in special patients: from bioanalysis to clinical relevanceFrom1 Oct 2021 → 30 Sep 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- An NMR facility tailored for biomedical researchFrom1 May 2020 → TodayFunding: FWO Medium Size Research Infrastructure
- Streamlining the route of phosphonate XNA from chemistry to applicationFrom1 Oct 2019 → 30 Sep 2023Funding: IOF - technology concept exploration, BOF - projects
- Directed evolution of bioactive compounds: Azol(in)e-containing post-translationally modified peptidesFrom1 Apr 2019 → 1 Apr 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Development of a comprehensive platform for targeting redox homeostasis in Mycobacterium tuberculosis.From1 Jan 2019 → 31 Dec 2022Funding: FWO research project (including WEAVE projects)
- Drug design strategies against newly emerging viral diseasesFrom17 Oct 2016 → 30 Oct 2020Funding: Own budget, for example: patrimony, inscription fees, gifts
- Development of XNA ligases as tools for synthetic biologyFrom22 Sep 2015 → 17 Oct 2019Funding: BOF - doctoral mandates, BOF - Doctoral projects
- Development of a xenozyme and an XNA ligase.From1 Oct 2014 → 30 Sep 2018Funding: BOF - Concerted Research Project from 1994
- Selection of nucleic acid chemistry for therapeutic aptamer design.From1 Jan 2014 → 31 Dec 2017Funding: FWO research project
- Oligonucleotides as biochemical and therapeutic tools.From1 Jan 2011 → 31 Dec 2014Funding: FWO research project
Publications
31 - 40 of 82
- Chemical Morphing of DNA Containing Four Noncanonical Bases(2016)
Authors: Elena Eremeeva, Mikhail Abramov, Jef Rozenski, Piet Herdewyn
Pages: 7515 - 7519 - Abl1 inhibitory contaminants leach from plastic tubes(2016)
Authors: Hui Chen, Bart Blanchaert, abhijit babaji Shinde, Erwin Adams, Jef Rozenski, Myriam Baes, Ann Van Schepdael
Pages: 340 - 343 - Characterization of insulin-degrading enzyme-mediated cleavage of A beta in distinct aggregation states(2016)
Authors: Jef Rozenski
Pages: 1281 - 1290 - Base pairing involving artificial bases in vitro and in vivo (vol 7, pg 995, 2016)(2016)
Authors: Omprakash Bande, Darren Braddick, Stefano Agnello, Miyeon Jang, Valerie Pezo, Guy Schepers, Jef Rozenski, Eveline Lescrinier, Philippe Marliere, Piet Herdewyn
Pages: 1611 - 1611 - Base pairing involving artificial bases in vitro and in vivo(2016)
Authors: Jef Rozenski, Eveline Lescrinier, Piet Herdewyn
Pages: 995 - 1010 - Achiral, acyclic nucleic acids: synthesis and biophysical studies of a possible prebiotic polymer(2015)
Authors: Puneet Srivastava, Rania Abou El Asrar, Mikhail Abramov, Mathy Froeyen, Jef Rozenski, Piet Herdewyn
Pages: 9249 - 60 - Aspartic acid based nucleoside phosphoramidate prodrugs as potent inhibitors of hepatitis C virus replication(2015)
Authors: Munmun Maiti, Mohitosh Maiti, Jef Rozenski, Steven De Jonghe, Piet Herdewyn
Pages: 5158 - 5174 - 5'-(N-aminoacyl)-sulfonamido-5'-deoxyadenosine: Attempts for a stable alternative for aminoacyl-sulfamoyl adenosines as aaRS inhibitors(2015)
Authors: Bharat Gadakh, Jef Rozenski, Mathy Froeyen, Arthur Van Aerschot
Pages: 227 - 236 - 5'-(N-aminoacyl)-sulfonamido-5'-deoxyadenosine: Attempts for a stable alternative for aminoacyl-sulfamoyl adenosines as aaRS inhibitors(2015)
Authors: Bharat Gadakh, Simon Smaers, Jef Rozenski, Mathy Froeyen, Arthur Van Aerschot
Pages: 227 - 36 - Isothiazolo[4,3-b]pyridines as inhibitors of cyclin G associated kinase: synthesis, structure-activity relationship studies and antiviral activity(2015)
Authors: Jef Rozenski, Steven De Jonghe, Piet Herdewyn
Pages: 1666 - 1672