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Project

Development of a xenozyme and an XNA ligase.

This research project has the aim to develop new artificial nucleic acids with a phosphonate group in the backbone, to develop ligases that may ligate such artificial nucleic acids and to use these synthetic nucleic acids to catalyze metabolic reactions.
Date:1 Oct 2014 →  30 Sep 2018
Keywords:phosphonates, nucleic acids, catalysis, metabolism, ligases, synthetic biology, Xenozyme
Disciplines:Biomarker discovery and evaluation, Drug discovery and development, Medicinal products, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences