< Back to previous page
Researcher
Jan Michiels
- Disciplines (Flanders Institute for Biotechnology):Auto-ecology, Biogeography and phylogeography, Anthropological genetics, Bacteriology, Biogeochemical cycli, Epigenomics
- Disciplines (KU Leuven):Biological system engineering
- See also: Jan Michiels (Flanders Institute for Biotechnology)
Affiliations
- Microbial and Plant Genetics (CMPG) (Division)
Responsible
From1 Aug 2020 → Today - Microbial and Plant Genetics (CMPG) (Division)
Member
From1 Aug 2020 → Today - Michiels Lab (Research group)
Responsible
From1 Oct 2017 → Today - Centre of Microbial and Plant Genetics (Division)
Member
From1 Aug 2005 → 31 Jul 2020
Projects
11 - 20 of 62
- PersiSTRESS: How the stress-resistance antiporter GadC integrates bacterial osmoregulation and pH homeostasis with antibiotic-tolerant persistenceFrom1 Oct 2021 → TodayFunding: FWO senior postdoctoral fellowship
- Cross-resistance and collateral sensitivity between human-targeted drugs and antibiotics in gut microbesFrom25 Mar 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Unraveling persister awakening mechanismsFrom1 Nov 2020 → 2 Oct 2022Funding: FWO junior postdoctoral fellowship
- Microbial cell factories to convert food waste into high-value chemicalsFrom1 Oct 2020 → TodayFunding: FWO Strategic Basic Research (SBO)
- Harnessing CRISPRi screening for unravelling genetic mechanisms underlying persistence in Escherichia coliFrom15 Sep 2020 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Discovery of novel antibiotics by highly-sensitive genotype-based high-throughput selection?From15 Sep 2020 → TodayFunding: FWO Strategic Basic Research Grant
- Investigating the mechanisms of drug persistence in Nontuberculous Mycobacteria and its impact on the emergence of resistanceFrom1 Sep 2020 → TodayFunding: Baekeland
- Making bacteria antibiotic-sensitive again: Towards understanding the genetic and physiological basis of persister cell awakeningFrom1 Jan 2020 → 31 Dec 2023Funding: FWO research project (including WEAVE projects)
- Bugs on drugs: the use of the Drosophila melanogaster gut microbiome to study bacterial antibiotic tolerance in a complex in vivo conditionFrom1 Jan 2020 → 31 Dec 2020Funding: FWO research grant KAN
- Unraveling molecular mechanisms controlling exit from the persister state and role of HokB homologues in mediating persistenceFrom13 Nov 2019 → 12 Nov 2020Funding: BOF - postdoctoral mandates
Publications
1 - 10 of 183
- Protocol for assessing single-cell persister recovery kinetics and physiology in Escherichia coli using spectrophotometry.(2024)
Authors: Sang Nguyen, Natalie Verstraeten, Jan Michiels
Pages: 102984 - A novel player in persistence: How protein aggregation allows bacteria to survive antibiotic treatment(2024)
Authors: Celien Bollen, Jan Michiels
- Bacillus subtilis as a host for natural product discovery and engineering of biosynthetic gene clusters(2024)
Authors: Hanne Put, Hans Gerstmans, Hanne Vande Capelle, Maarten Fauvart, Jan Michiels, Joleen Masschelein
- Exploring novel strategies to unravel the mechanisms underlying persister recovery in Escherichia coli(2024)
Authors: Elen Louwagie, Jan Michiels, Natalie Verstraeten, Liselot Dewachter
- Strigolactones repress nodule development and senescence in pea(2023)
Authors: Jan Michiels
Pages: 7 - 22 - A combined in vitro and in vivo approach to study persistence in natural Pseudomonas aeruginosa isolates(2023)
Authors: Laure Verstraete, Jan Michiels, Bram Van den Bergh
- Environmental, mechanistic and evolutionary landscape of antibiotic persistence(2023)
Authors: Celien Bollen, Elen Louwagie, Natalie Verstraeten, Jan Michiels, Philip Ruelens
- Genetic engineering of Escherichia coli to produce unsaturated fatty acids of medium chain length(2023)
Authors: Paul Matthay, Jan Michiels, Kristel Bernaerts, Natalie Verstraeten, Bert Sels
- In Vitro Persistence Level Reflects In Vivo Antibiotic Survival of Natural Pseudomonas aeruginosa Isolates in a Murine Lung Infection Model(2023)
Authors: Laure Verstraete, Rob Lavigne, Jan Michiels, Bram Van den Bergh
- Strategies to Enhance the Biosynthesis of Monounsaturated Fatty Acids in Escherichia coli(2023)
Authors: Paul Matthay, Thomas Schalck, Natalie Verstraeten, Jan Michiels
Pages: 36 - 50