Researcher
Liselot Dewachter
- Disciplines (Flanders Institute for Biotechnology):Auto-ecology, Biogeography and phylogeography, Anthropological genetics, Bacteriology, Biogeochemical cycli, Epigenomics
- Disciplines (KU Leuven):Biological system engineering
- See also: Liselot Dewachter (Flanders Institute for Biotechnology)
Affiliations
- Microbial and Plant Genetics (CMPG) (Division)
Member
From1 Aug 2020 → Today - Michiels Lab (Research group)
Member
From1 Oct 2017 → 30 Sep 2023 - Centre of Microbial and Plant Genetics (Division)
Member
From1 Oct 2013 → 31 Jul 2020
Projects
1 - 5 of 5
- Unraveling the essential role of the universally conserved GTPase Obg in bacteriaFrom1 Oct 2023 → 2 Oct 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Harnessing CRISPRi screening for unravelling genetic mechanisms underlying persistence in Escherichia coliFrom15 Sep 2020 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Cell envelope quality control by an essential GTPase as a novel cell cycle checkpoint in Escherichia coliFrom1 Oct 2018 → 30 Sep 2023Funding: FWO fellowships
- The role of ObgE in coordinating cell division and cell envelope formation in Escherichia coliFrom1 Nov 2017 → 31 Oct 2018Funding: BOF - Other initiatives
- A novel bacterial cell death pathway targeted by a poisoned cell cycle sentinelFrom1 Oct 2013 → 31 Oct 2017Funding: FWO fellowships
Publications
1 - 10 of 20
- Exploring novel strategies to unravel the mechanisms underlying persister recovery in Escherichia coli(2024)
Authors: Elen Louwagie, Jan Michiels, Natalie Verstraeten, Liselot Dewachter
- YbiB: a novel interactor of the GTPase ObgE(2023)
Authors: Silke Vercauteren, Liselot Dewachter, Natalie Verstraeten
Pages: 3420 - 3435 - Deep mutational scanning of essential bacterial proteins can guide antibiotic development(2023)
Authors: Liselot Dewachter, Thomas Schalck, Jan Michiels
- Amoxicillin-resistant Streptococcus pneumoniae can be resensitized by targeting the mevalonate pathway as indicated by sCRilecs-seq(2022)
Authors: Liselot Dewachter
- Mutations in respiratory complex I promote antibiotic persistence through alterations in intracellular acidity and protein synthesis(2022)
Authors: Bram Van den Bergh, Liselot Dewachter, Maarten Fauvart, Jan Michiels
Pages: 1 - 18 - The Dynamic Transition of Persistence toward the Viable but Nonculturable State during Stationary Phase Is Driven by Protein Aggregation(2021)
Authors: Liselot Dewachter, Celien Bollen, Dorien Wilmaerts, Elen Louwagie, Paul Matthay, Laleh Khodaparast, Ladan Khodaparast, Frederic Rousseau, Joost Schymkowitz, Jan Michiels
- Protein Aggregation as a Bacterial Strategy to Survive Antibiotic Treatment(2021)
Authors: Celien Bollen, Liselot Dewachter, Jan Michiels
- GTP Binding is Necessary for the Activation of a Toxic Mutant Isoform of the Essential GTPase ObgE(2019)
Authors: Liselot Dewachter, Pauline Herpels, Natalie Verstraeten, Maarten Fauvart, Jan Michiels
- Biochemical determinants of ObgE-mediated persistence(2019)
Authors: Natalie Verstraeten, Bram Van den Bergh, Pauline Herpels, Elen Louwagie, Dorien Wilmaerts, Liselot Dewachter, Maarten Fauvart, Jan Michiels
Pages: 1593 - 1608 - Bacterial Heterogeneity and Antibiotic Survival: Understanding and Combatting Persistence and Heteroresistance(2019)
Authors: Liselot Dewachter, Maarten Fauvart, Jan Michiels
Pages: 255 - 267