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Researcher
Jan Michiels
- Disciplines (Flanders Institute for Biotechnology):Auto-ecology, Biogeography and phylogeography, Anthropological genetics, Bacteriology, Biogeochemical cycli, Epigenomics
- Disciplines (KU Leuven):Biological system engineering
- See also: Jan Michiels (Flanders Institute for Biotechnology)
Affiliations
- Microbial and Plant Genetics (CMPG) (Division)
Responsible
From1 Aug 2020 → Today - Microbial and Plant Genetics (CMPG) (Division)
Member
From1 Aug 2020 → Today - Michiels Lab (Research group)
Responsible
From1 Oct 2017 → Today - Centre of Microbial and Plant Genetics (Division)
Member
From1 Aug 2005 → 31 Jul 2020
Projects
31 - 40 of 62
- Ethanol tolerance engineering in ethanologenic bacteria.From1 Jan 2017 → 24 Jun 2021Funding: FWO Strategic Basic Research Grant
- In vivo multidrug-tolerant persister cells and their evolution in the face of antibiotic treatment: genetic and physiological adaptation mechanismsFrom1 Jan 2017 → 31 Dec 2020Funding: FWO research project (including WEAVE projects)
- Bacterial persistence, the adaptive landscape of multidrug tolerance and its in vivo relevance in the face of antibiotic treatmentsFrom1 Oct 2016 → 30 Sep 2021Funding: FWO fellowships
- An analytical pipeline for microbial proteins: from peptide to multi-protein complexes in single cells and populationsFrom1 Oct 2016 → 30 Sep 2018Funding: Fund Recuperation Fiscal Exemption
- Disecting bacterial persistence through experimental evolution: memory, persister physiology and the link with genetic resistanceFrom9 Sep 2016 → 12 Jan 2021Funding: FWO fellowships
- 3D dynamic super-resolution imaging of bacterial lysis.From17 Nov 2015 → 16 Nov 2016Funding: BOF - Other initiatives
- Persister cells under the magnifying glass: drafting a persister model and development of persistence diagnostics markersFrom4 Nov 2015 → 10 Jun 2020Funding: FWO Strategic Basic Research Grant
- Mechanistic insights in HokB-mediated persister formation and awakeningFrom26 Aug 2015 → 12 Nov 2019Funding: BOF - Doctoral projects
- Elucidating the role of two novel toxin-antitoxin modules in Escherichia coli multidrug tolerance.From1 Jan 2015 → 31 Dec 2018Funding: FWO research project (including WEAVE projects)
- Study of β-lactam induced bacteriolysis using high-throughput time-resolved microscopy and mechanical bacteriolysis by nanostructured surfacesFrom1 Oct 2014 → 30 Aug 2019Funding: BOF - Doctoral projects
Publications
1 - 10 of 183
- Protocol for assessing single-cell persister recovery kinetics and physiology in Escherichia coli using spectrophotometry.(2024)
Authors: Sang Nguyen, Natalie Verstraeten, Jan Michiels
Pages: 102984 - A novel player in persistence: How protein aggregation allows bacteria to survive antibiotic treatment(2024)
Authors: Celien Bollen, Jan Michiels
- Bacillus subtilis as a host for natural product discovery and engineering of biosynthetic gene clusters(2024)
Authors: Hanne Put, Hans Gerstmans, Hanne Vande Capelle, Maarten Fauvart, Jan Michiels, Joleen Masschelein
- Exploring novel strategies to unravel the mechanisms underlying persister recovery in Escherichia coli(2024)
Authors: Elen Louwagie, Jan Michiels, Natalie Verstraeten, Liselot Dewachter
- Strigolactones repress nodule development and senescence in pea(2023)
Authors: Jan Michiels
Pages: 7 - 22 - A combined in vitro and in vivo approach to study persistence in natural Pseudomonas aeruginosa isolates(2023)
Authors: Laure Verstraete, Jan Michiels, Bram Van den Bergh
- Environmental, mechanistic and evolutionary landscape of antibiotic persistence(2023)
Authors: Celien Bollen, Elen Louwagie, Natalie Verstraeten, Jan Michiels, Philip Ruelens
- Genetic engineering of Escherichia coli to produce unsaturated fatty acids of medium chain length(2023)
Authors: Paul Matthay, Jan Michiels, Kristel Bernaerts, Natalie Verstraeten, Bert Sels
- In Vitro Persistence Level Reflects In Vivo Antibiotic Survival of Natural Pseudomonas aeruginosa Isolates in a Murine Lung Infection Model(2023)
Authors: Laure Verstraete, Rob Lavigne, Jan Michiels, Bram Van den Bergh
- Strategies to Enhance the Biosynthesis of Monounsaturated Fatty Acids in Escherichia coli(2023)
Authors: Paul Matthay, Thomas Schalck, Natalie Verstraeten, Jan Michiels
Pages: 36 - 50