Researcher
Hilde Brems
- Disciplines:Genetics, Systems biology, Medical imaging and therapy, Molecular and cell biology, Other paramedical sciences
Affiliations
- Laboratory for Neurofibromatosis Research (Division)
Responsible
From15 Jul 2022 → Today - Laboratory for Neurofibromatosis Research (Division)
Member
From19 Oct 2009 → 30 Sep 2017 - Department of Human Genetics (Department)
Member
From1 Oct 1999 → Today
Projects
1 - 7 of 7
- Molecular and functional characterization of Legius syndrome and related disorders: Improved diagnosis and understanding of the underlying mechanisms.From1 Aug 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Development of new analytic tools and pathways to accelerate diagnosis and facilitate diagnostic monitoring of rare diseases”From1 Aug 2023 → TodayFunding: FWO research project (including WEAVE projects)
- Importance of SPRED1 in melanomaFrom9 Dec 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Importance of SPRED1 in melanomaFrom1 Oct 2015 → 27 Mar 2020Funding: Own budget, for example: patrimony, inscription fees, gifts
- Periosteal cell therapy as a new treatment of pseudarthrosis in children with NF1.From21 Oct 2013 → 10 Dec 2019Funding: IWT personal funding - strategic basic research grants, BOF - Doctoral projects
- Pathogenesis of congenital tibial bowing and pseudarthrosis in neurofibromatosis type 1.From1 Jan 2012 → 31 Dec 2015Funding: FWO research project
- NF1-like syndromes: identification of new genes and further characterization of Legius syndrome using the mouse model.From1 Oct 2011 → 30 Sep 2017Funding: FWO fellowships
Publications
61 - 70 of 84
- Multiple pilomatricomas with somatic CTNNB1 mutations in children with constitutive mismatch repair deficiency(2013)
Authors: Magdalena Chmara, Bartosz Wasag, Hilde Peeters, Eline Beert, Hilde Brems, Raf Sciot, Eric Legius
Pages: 656 - 664 - Neurofibroma (including variants)(2013)
Authors: Christina R Antonescu, Hilde Brems, Eric Legius, James M Woodruff, Christopher DM Fletcher, Julia A Bridge, Pancreas CW Hogendoorn, Frederik Mertens
Pages: 174 - 176 - Neurofibromatosis type 1(2013)
Authors: Hilde Brems, Eric Legius, Christopher DM Fletcher, Julia A Bridge, Pancreas CW Hogendoorn, Frederik Mertens
Pages: 386 - 387 - Molecular Genetics of Neurofibromatosis type 1 and SPRED1(2013)
Authors: Hilde Brems, Eric Legius
Pages: 354 - Glomus tumours(2013)
Authors: Andrew L Folpe, Hilde Brems, Eric Legius, Christopher DM Fletcher, Julia A Bridge, Pancreas CW Hogendoorn, Frederik Mertens
Pages: 116 - 117 - Review and update of SPRED1 mutations causing legius syndrome(2012)
Authors: Hilde Brems, Eric Legius, Ludwine Messiaen
Pages: 1538 - 1546 - Biallelic inactivation of NF1 in a sporadic plexiform neurofibroma(2012)
Authors: Eline Beert, Hilde Brems, Julio Finalet Ferreiro, Ivo De Wever, Raf Sciot, Eric Legius, Maria Debiec-Rychter
Pages: 852 - 857 - Multiple orbital neurofibromas, painful peripheral nerve tumors, distinctive face and marfanoid habitus: a new syndrome(2012)
Authors: Ludwine Messiaen, Hilde Brems, Ellen Denayer, Raf Sciot, Eline Beert, Frank Van Calenbergh, Eric Legius
Pages: 618 - 625 - Mitotic recombination of chromosome arm 17q as a cause of loss of heterozygosity of NF1 in neurofibromatosis type 1-associated glomus tumors(2012)
Authors: Peter Van Loo, Eline Beert, Hilde Brems, Raf Sciot, Eric Legius
Pages: 429 - 437 - Exploring the somatic NF1 mutational spectrum associated with NF1 cutaneous neurofibromas(2012)
Authors: Hilde Brems, Eric Legius
Pages: 411 - 419