Researcher
Geert Berx
- Keywords:Metastasis, Cancer, EMT
- Disciplines:Transcription and translation, Cancer therapy, Cellular interactions and extracellular matrix, Cell movement, Cell signalling, Epigenetics, Genetics, Cancer biology
Affiliations
- Department of Biomedical molecular biology (Department)
Member
From1 Jan 1996 → Today - Department of Plant Biotechnology and Bioinformatics (Department)
Member
From1 Feb 1993 → 31 Dec 1995
Projects
1 - 10 of 21
- Unraveling the molecular regulation of ZEB driven melanoma plasticity as a basis for anti-melanoma therapyFrom1 Nov 2023 → TodayFunding: FWO Strategic Basic Research Grant
- Dissecting stromal-cancer cell interactions at the perivascular niche to detect and intercept the early metastatic process.From1 Jan 2023 → TodayFunding: BOF - iBOF
- Unbiased exploration of epithelial-mesenchymal plasticity in colorectal cancer reveals role for non-canonical STAT1 signallingFrom1 Nov 2022 → TodayFunding: FWO fellowships
- A patient derived xenograft (PDX) platform for in vivo evaluation of novel anticancer therapiesFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- SpatialConnect: linking tissue biology to the new era of single-cell spatial transcriptomicsFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- An alternative more tolerable L-asparaginase variant for the treatment of metastatic breast cancerFrom1 Nov 2021 → TodayFunding: FWO Strategic Basic Research Grant
- The use of a less toxic alternative asparaginase variant to treat metastatic breast cancerFrom1 Oct 2021 → TodayFunding: BOF - projects
- Defining the role of ZEB1 in tumour initiation and progression of basal-like breast cancerFrom1 Mar 2021 → TodayFunding: Foundations, funds and other with scientific goal
- Targeting the Tumor Microenvironment in Colorectal Peritoneal MetastasesFrom1 Jan 2021 → TodayFunding: BOF - projects
- The peritoneal microenvironment in the pathogenesis of colorectal peritoneal carcinomatosis: the role of MMT and cancer-associated fibroblastsFrom1 Nov 2020 → TodayFunding: FWO fellowships
Publications
21 - 30 of 43
- BRD4 inhibition improves the efficacy of ABT-199 in T-cell acute lymphoblastic leukemia(2016)Volume: 76
Authors: Sofie Peirs, Filip Matthijssens, Tim Pieters, Niels Vandamme, Geert Berx, Bruce Poppe, Pieter Van Vlierberghe
Number of pages: 1 - Targeting BET family proteins improves the therapeutic efficacy of BCL-2 inhibition in T-cell acute lymphoblastic leukemia(2016)Volume: 101
Authors: Sofie Peirs, Viktoras Frismantas, Filip Matthijssens, Béatrice Lintermans, Tim Pieters, Niels Vandamme, Wouter Van Loocke, Geert Berx, Bruce Poppe, Jean-Pierre Bourquin, et al.
Pages: 201 - 202 - Genetic characterization and therapeutic targeting of MYC translocated pediatric T-cell acute lymphoblastic leukemia(2016)Volume: 76
Authors: Gloria Milani, Kaat Durinck, Filip Matthijssens, Sofie Peirs, Tim Pieters, Lindy Reunes, Béatrice Lintermans, Niels Vandamme, Tim Lammens, Yunlei Li, et al.
Number of pages: 1 - Interplay between KLF4 and ZEB2/SIP1 in the regulation of E-cadherin expression(2013)
Authors: Benjamin Koopmansch, Geert Berx, Jean-Michel Foidart, Christine Gilles, Rosita Winkler
Pages: 652 - 657 - Concepts of metastasis in flux: the stromal progression model(2012)
Authors: Jonathan P Sleeman, Gerhard Christofori, Riccardo Fodde, John G Collard, Geert Berx, Charles Decraene, Curzio Rüegg
Pages: 174 - 186 - Module network inference from a cancer gene expression data set identifies microRNA regulated modules(2010)
Authors: Eric Bonnet, Marianthi Tatari, Anagha Joshi, Tom Michoel, Kathleen Marchal, Geert Berx, Yves Van de Peer
- Regulation of p63 isoforms by snail and slug transcription factors in human squamous cell carcinoma(2010)
Authors: Michael Herfs, Pascale Hubert, Meggy Suarez-Carmona, Anca Reschner, Sven Saussez, Geert Berx, Pierre Savagner, Jacques Boniver, Philippe Delvenne
Pages: 1941 - 1949 - The cell-cell adhesion molecule E-cadherin(2008)
Authors: Frans Van Roy, Geert Berx
Pages: 3756 - 3788 - Transforming growth factor-beta 1-mediated slug and snail transcription factor up-regulation reduces the density of Langerhans cells in epithelial metaplasia by affecting E-cadherin expression(2008)
Authors: M HERFS, P HUBERT, N KHOLOD, JH CABERG, C GILLES, Geert Berx, P SAVAGNER, J BONIVER, P DELVENNE
Pages: 1391 - 1402 - Molecular and pathological signatures of epithelial-mesenchymal transitions at the cancer invasion front(2008)
Authors: Olivier De Wever, Patrick Pauwels, Bram De Craene, M SABBAH, S EMAMI, G REDEUILH, C GESPACH, Marc Bracke, Geert Berx
Pages: 481 - 494