Researcher
Geert Berx
- Keywords:Metastasis, Cancer, EMT
- Disciplines:Transcription and translation, Cancer therapy, Cellular interactions and extracellular matrix, Cell movement, Cell signalling, Epigenetics, Genetics, Cancer biology
Affiliations
- Department of Biomedical molecular biology (Department)
Member
From1 Jan 1996 → Today - Department of Plant Biotechnology and Bioinformatics (Department)
Member
From1 Feb 1993 → 31 Dec 1995
Projects
1 - 10 of 21
- Unraveling the molecular regulation of ZEB driven melanoma plasticity as a basis for anti-melanoma therapyFrom1 Nov 2023 → TodayFunding: FWO Strategic Basic Research Grant
- Dissecting stromal-cancer cell interactions at the perivascular niche to detect and intercept the early metastatic process.From1 Jan 2023 → TodayFunding: BOF - iBOF
- Unbiased exploration of epithelial-mesenchymal plasticity in colorectal cancer reveals role for non-canonical STAT1 signallingFrom1 Nov 2022 → TodayFunding: FWO fellowships
- A patient derived xenograft (PDX) platform for in vivo evaluation of novel anticancer therapiesFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- SpatialConnect: linking tissue biology to the new era of single-cell spatial transcriptomicsFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- An alternative more tolerable L-asparaginase variant for the treatment of metastatic breast cancerFrom1 Nov 2021 → TodayFunding: FWO Strategic Basic Research Grant
- The use of a less toxic alternative asparaginase variant to treat metastatic breast cancerFrom1 Oct 2021 → TodayFunding: BOF - projects
- Defining the role of ZEB1 in tumour initiation and progression of basal-like breast cancerFrom1 Mar 2021 → TodayFunding: Foundations, funds and other with scientific goal
- Targeting the Tumor Microenvironment in Colorectal Peritoneal MetastasesFrom1 Jan 2021 → TodayFunding: BOF - projects
- The peritoneal microenvironment in the pathogenesis of colorectal peritoneal carcinomatosis: the role of MMT and cancer-associated fibroblastsFrom1 Nov 2020 → TodayFunding: FWO fellowships
Publications
11 - 20 of 43
- Guidelines and definitions for research on epithelialU+2013mesenchymal transition(2020)
Authors: Jing Yang, Parker Antin, Geert Berx, Cédric Blanpain, Thomas Brabletz, Marianne Bronner, Kyra Campbell, Amparo Cano, Jordi Casanova, Gerhard Christofori, et al.
Pages: 341 - 352 - A new mouse model to study the role of ectopic Nanos3 expression in cancer(2019)
Authors: Vanessa Andries, Evi De Keuckelaere, Katrien Staes, Tino Hochepied, Joachim Taminau, Kelly Lemeire, Philippe Birembaut, Geert Berx, Frans Van Roy
- Tumor engineering a clinical relevant model that recapitulates the tumor environment of peritoneal metastases in vitro and in vivo(2019)
Authors: Elly De Vlieghere, Emiel De Jaeghere, Glenn Wagemans, Thibaut Van Acker, Christian Vanhove, Geert Berx, Frank Vanhaecke, Wim Ceelen, Bruno De Geest, Heidi Declercq, et al.
Number of pages: 1 - An Ovol2‐Zeb1 transcriptional circuit regulates epithelial directional migration and proliferation(2019)
Authors: Daniel Haensel, Peng Sun, Adam L MacLean, Xianghui Ma, Yuan Zhou, Marc P Stemmler, Simone Brabletz, Geert Berx, Maksim V Plikus, Qing Nie, et al.
- The role of epithelial-to-mesenchymal plasticity in ovarian cancer progression and therapy resistance(2019)
Authors: Nele Loret, Hannelore Denys, Philippe Tummers, Geert Berx
- Xenogen-free isolation and culture of human adipose mesenchymal stem cells(2019)
Authors: Maarten Doornaert, Elisabeth De Maere, Julien Colle, Heidi Declercq, Joachim Taminau, Kelly Lemeire, Geert Berx, Phillip Blondeel
- ZEB2 in T-cells and T-ALL(2019)
Authors: Stien De Coninck, Geert Berx, Tom Taghon, Pieter Van Vlierberghe, Steven Goossens
- ZEB2 stably represses RAB25 expression through epigenetic regulation by SIRT1 and DNMTs during epithelial-to-mesenchymal transition(2018)
Authors: Nicolas Skrypek, Kenneth Bruneel, Cindy Vandewalle, Eva De Smedt, Bieke Soen, Nele Loret, Joachim Taminau, Steven Goossens, Niels Vandamme, Geert Berx
- ZEB proteins in leukemia : friends, foes, or friendly foes?(2018)
Authors: Bieke Soen, Niels Vandamme, Geert Berx, Jürg Schwaller, Pieter Van Vlierberghe, Steven Goossens
- Structure-function studies in mouse embryonic stem cells using recombinase-mediated cassette exchange(2017)
Authors: Tim Pieters, Lieven Haenebalcke, Kenneth Bruneel, Niels Vandamme, Tino Hochepied, Jolanda van Hengel, Dagmar Wirth, Geert Berx, Jody J Haigh, Frans Van Roy, et al.