Researcher
Geert Berx
- Keywords:Metastasis, Cancer, EMT
- Disciplines:Transcription and translation, Cancer therapy, Cellular interactions and extracellular matrix, Cell movement, Cell signalling, Epigenetics, Genetics, Cancer biology
Affiliations
- Department of Biomedical molecular biology (Department)
Member
From1 Jan 1996 → Today - Department of Plant Biotechnology and Bioinformatics (Department)
Member
From1 Feb 1993 → 31 Dec 1995
Projects
1 - 10 of 21
- Unraveling the molecular regulation of ZEB driven melanoma plasticity as a basis for anti-melanoma therapyFrom1 Nov 2023 → TodayFunding: FWO Strategic Basic Research Grant
- Dissecting stromal-cancer cell interactions at the perivascular niche to detect and intercept the early metastatic process.From1 Jan 2023 → TodayFunding: BOF - iBOF
- Unbiased exploration of epithelial-mesenchymal plasticity in colorectal cancer reveals role for non-canonical STAT1 signallingFrom1 Nov 2022 → TodayFunding: FWO fellowships
- A patient derived xenograft (PDX) platform for in vivo evaluation of novel anticancer therapiesFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- SpatialConnect: linking tissue biology to the new era of single-cell spatial transcriptomicsFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- An alternative more tolerable L-asparaginase variant for the treatment of metastatic breast cancerFrom1 Nov 2021 → TodayFunding: FWO Strategic Basic Research Grant
- The use of a less toxic alternative asparaginase variant to treat metastatic breast cancerFrom1 Oct 2021 → TodayFunding: BOF - projects
- Defining the role of ZEB1 in tumour initiation and progression of basal-like breast cancerFrom1 Mar 2021 → TodayFunding: Foundations, funds and other with scientific goal
- Targeting the Tumor Microenvironment in Colorectal Peritoneal MetastasesFrom1 Jan 2021 → TodayFunding: BOF - projects
- The peritoneal microenvironment in the pathogenesis of colorectal peritoneal carcinomatosis: the role of MMT and cancer-associated fibroblastsFrom1 Nov 2020 → TodayFunding: FWO fellowships
Publications
31 - 40 of 43
- Snail promotes Wnt target gene expression and interacts with beta-catenin(2008)
Authors: V STEMMER, Bram De Craene, Geert Berx, J BEHRENS
Pages: 5075 - 5080 - Involvement of members of the Cadherin superfamily in cancer
Authors: Geert Berx, Frans Van Roy
- Regulatory networks defining EMT during cancer initiation and progression
Authors: Bram De Craene, Geert Berx
Pages: 97 - 110 - Development and characterization of a new human hepatic cell line
Authors: Eva Ramboer, Bram De Craene, Joey De Kock, Geert Berx, Vera Rogiers, Tamara Vanhaecke, Mathieu Vinken
Pages: 875 - 889 - Epithelial-mesenchymal transition (EMT) as a therapeutic target
Authors: Sven Jonckheere, Jamie Adams, Dominic De Groote, Kyra Campbell, Geert Berx
Pages: 157 - 182 - Key signalling nodes in mammary gland development and cancer: the snail1-twist1 conspiracy in malignant breast cancer progression
Authors: Ellen Foubert, Bram De Craene, Geert Berx
- Evolutionary functional analysis and molecular regulation of the ZEB transcription factors
Authors: Alexander Gheldof, Frans Van Roy, Bram De Craene, Geert Berx
Pages: 2527 - 2541 - Strategies for immortalization of primary hepatocytes
Authors: Eva Ramboer, Bram De Craene, Joery De Kock, Tamara Vanhaecke, Geert Berx, Vera Rogiers, Mathieu Vinken
Pages: 925 - 943 - Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium
Authors: Katja Horvay, Thierry Jardé, Franca Casagranda, Victoria M Perreau, Katharina Haigh, Christian M Nefzger, Reyhan Akhtar, Thomas Gridley, Geert Berx, Jody Haigh, et al.
Pages: 1319 - 1335 - Gene expression profiling to dissect the complexity of cancer biology: pitfalls and promise
Authors: Eric Raspé, Charles Decraene, Geert Berx
Pages: 250 - 260