Researcher
Geert Berx
- Keywords:Metastasis, Cancer, EMT
- Disciplines:Transcription and translation, Cancer therapy, Cellular interactions and extracellular matrix, Cell movement, Cell signalling, Epigenetics, Genetics, Cancer biology
Affiliations
- Department of Biomedical molecular biology (Department)
Member
From1 Jan 1996 → Today - Department of Plant Biotechnology and Bioinformatics (Department)
Member
From1 Feb 1993 → 31 Dec 1995
Projects
11 - 20 of 21
- In vivo analysis of the role of EMT in triple-negative breast cancer initiation and immune modulation.From1 Nov 2019 → 31 Dec 2022Funding: FWO fellowships
- The role of ZEB1 in basal breast cancerFrom1 Oct 2017 → 31 Mar 2018Funding: Foundations, funds and other with scientific goal
- The role of ZEB transcription factors in epigenetic chromatin remodeling and gene expression regulation during EMTFrom1 Jan 2017 → 31 Dec 2019Funding: FWO research project (including WEAVE projects)
- The role of ZEB transcription factors in malignant progression and therapy resistance in high grade serous ovarian cancerFrom1 Oct 2016 → 15 May 2021Funding: BOF - Doctoral projects
- ZEB1 drives melanoma development by bypassing oncogene-induced senescence in melanocytic neviFrom1 Jan 2016 → 31 Dec 2016Funding: FWO Humanitarian research project Stand up against Cancer
- Identification and characterization of residual melanoma cells to MAPL-targeted therapy: a search for biomarkers and novel therapeutic opportunitiesFrom1 Sep 2014 → 31 Aug 2018Funding: FWO Humanitarian research project Stand up against Cancer
- Roles of Nanos family members in cancer progressionFrom1 Jan 2013 → 31 Dec 2016Funding: Foundations, funds and other with scientific goal
- Towards improved genetic diagnosis for hereditary breast and ovarian cancer: evolution and challengesFrom1 Jan 2013 → 31 Dec 2016Funding: Foundations, funds and other with scientific goal
- EMT, stem cells and inflammation: a malignant cocktail for cancerFrom1 Jan 2012 → 31 Oct 2016Funding: BOF - Doctoral projects
- Structural and functional characterization of class-II classic cadherins end delta-protocadherinsFrom1 Jul 2011 → 30 Apr 2016Funding: BOF - Doctoral projects
Publications
1 - 10 of 43
- Laser-induced vapor nanobubbles for B16-F10 melanoma cell killing and intracellular delivery of chemotherapeutics(2024)
Authors: Jana Ramon, Yanou Engelen, Herlinde De Keersmaecker, Ilia Goemaere, Deep Punj, Julián Mejía Morales, Cédric Bonte, Geert Berx, Esther Hoste, Stephan Stremersch, et al.
Pages: 1019 - 1036 - A role for partial epithelial-to-mesenchymal transition in enabling stemness in homeostasis and cancer(2023)
Authors: Jeroen Verstappe, Geert Berx
Pages: 15 - 28 - The epithelial-mesenchymal plasticity landscape: principles of design and mechanisms of regulation(2023)
Authors: Jef Haerinck, Steven Goossens, Geert Berx
Pages: 590 - 609 - Coordinate control of basal epithelial cell fate and stem cell maintenance by core EMT transcription factor Zeb1(2022)
Authors: Yingying Han, Alvaro Villarreal-Ponce, Guadalupe Gutierrez, Quy Nguyen, Peng Sun, Ting Wu, Benjamin Sui, Geert Berx, Thomas Brabletz, Kai Kessenbrock, et al.
- Pancreas morphogenesis and homeostasis depends on tightly regulated Zeb1 levels in epithelial cells(2021)
Authors: Maria Lasierra Losada, Melissa Pauler, Niels Vandamme, Steven Goossens, Geert Berx, Moritz Leppkes, Harald Schuhwerk, Simone Brabletz, Thomas Brabletz, Marc P. Stemmler
- The ZEB2-dependent EMT transcriptional programme drives therapy resistance by activating nucleotide excision repair genes ERCC1 and ERCC4 in colorectal cancer(2021)
Authors: Rahul Sreekumar, Hajir Al-Saihati, Muhammad Emaduddin, Karwan Moutasim, Massimiliano Mellone, Ashish Patel, Seval Kilic, Metin Cetin, Sule Erdemir, Marta Salgado Navio, et al.
Pages: 2065 - 2083 - Interplay between the EMT transcription factors ZEB1 and ZEB2 regulates hematopoietic stem and progenitor cell differentiation and hematopoietic lineage fidelity(2021)
Authors: Jueqiong Wang, Carlos Farkas, Aissa Benyoucef, Catherine Carmichael, Katharina Haigh, Nick Wong, Danny Huylebroeck, Marc P. Stemmler, Simone Brabletz, Thomas Brabletz, et al.
- Partial EMT takes the lead in cancer metastasis(2021)
Authors: Jef Haerinck, Geert Berx
Pages: 3174 - 3176 - The EMT transcription factor ZEB1 blocks osteoblastic differentiation in bone development and osteosarcoma(2021)
Authors: Manuel Ruh, Marc P. Stemmler, Isabell Frisch, Kathrin Fuchs, Ruthger Roey, Julia Kleemann, Maike Roas, Harald Schuhwerk, Rebecca L. Eccles, Abbas Agaimy, et al.
Pages: 199 - 211 - Establishment and characterization of a cell line and patient-derived xenograft (PDX) from peritoneal metastasis of low-grade serous ovarian carcinoma(2020)
Authors: Elien De Thaye, Koen Van de Vijver, Joni Van der Meulen, Joachim Taminau, Glenn Wagemans, Hannelore Denys, Jo Van Dorpe, Geert Berx, Wim Ceelen, Jan Van Bocxlaer, et al.