Researcher
Dries Knapen
- Research Expertise:Aquatic toxicology, zebrafish, adverse outcome pathways, stress physiology, systems biology, developmental biology, embryonic development, alternative testing approaches
- Keywords:ECOTOXICOLOGY, FISH ECOTOXICOLOGY, TOXICOLOGY, REPRODUCTIVE PHYSIOLOGY AND TOXICITY, ENVIRONMENTAL TOXICOLOGY, EMBRYOTOXICITY, Biology
- Disciplines:Environmental impact and risk assessment
- Research techniques:Zebrafish embryo test, zebrafish test, alternative in chemico and in vitro tests
- Users of research expertise:Toxicology, ecotoxicology
Affiliations
- Veterinary physiology and biochemistry (Research group)
Member
From1 Oct 2010 → Today - Systemic Physiological and Ecotoxicological Research (SPHERE) (Research group)
Member
From1 Oct 2003 → 30 Sep 2010
Projects
1 - 10 of 37
- Development of a mechanistic Integrated Approaches for Testing and Assessment (IATA) model for the identification of thyroid hormone system disrupting chemicals.From1 Nov 2023 → TodayFunding: FOD Public Health, Safety of the food chain and the Environment
- Partnership for the Assessment of Risks from Chemicals (PARC).From1 May 2022 → TodayFunding: HORIZON.2.1 - Health
- Vital crop growth through usage of microalgaebased biostimulants (VIGOROUS).From1 Oct 2021 → TodayFunding: FWO Strategic Basic Research (SBO)
- Thyroid hormone system disruption during early and late zebrafish embryo development.From1 Oct 2021 → TodayFunding: BOF - doctoral mandates
- Elucidating the pathogenicity of genetic variants of uncertain significance in Brugada syndrome patients by functional modelling in hiPSC-derived cardiomyocytes and zebrafish.From1 Nov 2020 → TodayFunding: FWO fellowships
- SPHERE LAB: An accredited body for ecotoxicological risk assessment.From1 Sep 2020 → 31 Aug 2021Funding: IOF - technology validation in real environment
- Development of a guidance document for improving zebrafish welfare in laboratory animal facilities.From1 Sep 2020 → 31 Jan 2023Funding: Department of Environment
- From exposome to effect assessment of contaminants in human and animal models (EXPOSOME).From1 Jan 2020 → TodayFunding: BOF - research organisations, Fund Recuperation Fiscal Exemption
- An integrated multi-purpose basic infrastructure for dynamic and sensitive metabolic profiling of cells and embryos.From1 Jan 2020 → 31 Dec 2021Funding: BOF - scientific equipment program
- Breaking down the wall between human health and environmental testing of endocrine disrupters: EndocRine Guideline Optimisation (ERGO).From1 Jan 2019 → TodayFunding: H2020-EU.3.1. - SOCIETAL CHALLENGES - Health, demographic change and wellbeing
Publications
11 - 20 of 107
- Thyroperoxidase inhibition leading to increased mortality via reduced anterior swim bladder inflation(2022)Series: OECD series on adverse outcome
Authors: Lucia Vergauwen, Evelyn Stinckens, Daniel L. Villeneuve, Dries Knapen
Number of pages: 124 - Deiodinase 2 inhibition leading to increased mortality via reduced anterior swim bladder inflation(2022)Series: OECD series on adverse outcome
Authors: Lucia Vergauwen, Evelyn Stinckens, Daniel L. Villeneuve, Dries Knapen
Number of pages: 66 - Deiodinase 1 inhibition leading to increased mortality via reduced posterior swim bladder inflation(2022)Series: OECD series on adverse outcome
Authors: Lucia Vergauwen, Evelyn Stinckens, Daniel L. Villeneuve, Dries Knapen
Number of pages: 24 - Deiodinase 2 inhibition leading to increased mortality via reduced posterior swim bladder inflation(2022)Series: OECD series on adverse outcome
Authors: Lucia Vergauwen, Evelyn Stinckens, Daniel L. Villeneuve, Dries Knapen
Number of pages: 88 - AOP report(2022)
Authors: Lisa Gölz, Lisa Baumann, Pauline Pannetier, Thomas Braunbeck, Dries Knapen, Lucia Vergauwen
Pages: 2632 - 2648 - Lipidomics profiling of zebrafish liver through untargeted liquid chromatography‐high resolution mass spectrometry(2022)
Authors: Katyeny Manuela Da Silva, Elias Iturrospe, Rik van den Boom, Maria van de Lavoir, Rani Robeyns, Lucia Vergauwen, Dries Knapen, Matthias Cuykx, Adrian Covaci, Alexander van Nuijs
Pages: 2935 - 2945 - Deiodinase 1 inhibition leading to increased mortality via reduced anterior swim bladder inflation(2022)Series: OECD series on adverse outcome
Authors: Lucia Vergauwen, Evelyn Stinckens, Daniel L. Villeneuve, Dries Knapen
Number of pages: 67 - Evidenced-based approaches to support the development of endocrine-mediated adverse outcome pathways(2021)
Authors: Karine Audouze, Elias Zgheib, Khaled Abass, Asma H. Baig, Isabel Forner-Piquer, Henrik Holbech, Dries Knapen, Pim E.G. Leonards, Diana I. Lupu, Saranya Palaniswamy, et al.
- A pragmatic approach to adverse outcome pathway development and evaluation(2021)
Authors: Terje Svingen, Daniel L. Villeneuve, Dries Knapen, Eleftheria Maria Panagiotou, Monica Kam Draskau, Pauliina Damdimopoulou, Jason M. O’Brien
Pages: 183 - 190 - Adverse outcome pathways and the paradox of complex simplicity(2021)
Authors: Dries Knapen
Pages: 2950 - 2952