Researcher
Dries Knapen
- Research Expertise:Aquatic toxicology, zebrafish, adverse outcome pathways, stress physiology, systems biology, developmental biology, embryonic development, alternative testing approaches
- Keywords:ECOTOXICOLOGY, FISH ECOTOXICOLOGY, TOXICOLOGY, REPRODUCTIVE PHYSIOLOGY AND TOXICITY, ENVIRONMENTAL TOXICOLOGY, EMBRYOTOXICITY, Biology
- Disciplines:Environmental impact and risk assessment
- Research techniques:Zebrafish embryo test, zebrafish test, alternative in chemico and in vitro tests
- Users of research expertise:Toxicology, ecotoxicology
Affiliations
- Veterinary physiology and biochemistry (Research group)
Member
From1 Oct 2010 → Today - Systemic Physiological and Ecotoxicological Research (SPHERE) (Research group)
Member
From1 Oct 2003 → 30 Sep 2010
Projects
11 - 20 of 37
- Study Contract 'Development of a study protocol for regulatory testing to identify endocrine disrupting substances in biotic systems'.From1 Jan 2019 → 20 Jan 2022Funding: EU - out of framework - indefinite
- The role of the paraoxonase gene family in obesity and obesity-associated liver disease following exposure to environmental pollutants or medical intervention strategies.From1 Jan 2019 → 31 Dec 2022Funding: BOF - projects
- Metal mixture toxicity and defense mechanisms in zebrafish and other model species.From1 Oct 2018 → 31 Dec 2019Funding: Fund Recuperation Fiscal Exemption
- Development of a functional assay to determine the pathogenicity of genetic variants with unknown significance identified in patients with cardiac arrhythmia.From1 Oct 2018 → 30 Sep 2022Funding: FWO fellowships
- Unravelling the non-specific mechanisms underlying non-polar narcotic toxicity: mitochondrial effects.From1 Jan 2017 → 31 Dec 2020Funding: FWO research project (including WEAVE projects)
- Modular confocal microscopy platform with light sheet illumination.From1 May 2016 → 30 Apr 2020Funding: Own budget, for example: patrimony, inscription fees, gifts, FWO Medium Size Research Infrastructure
- Development of an alternative testing strategy for the fish early-life stage test for predicting chronic toxicity : assay validation.From1 Mar 2016 → 28 Feb 2018Funding: Foreign Nonprofit organisations and equivalents
- An alternative testing strategy for the fish early life-stage test using the adverse outcome pathway (AOP) framework.From1 Jan 2016 → 31 Dec 2016Funding: Foreign Nonprofit organisations and equivalents
- The impact of endocrine disruption on vertebrate embryonic and larval development.From1 Oct 2015 → 30 Sep 2019Funding: BOF - Doctoral projects
- Development of a zebrafish embryo test for environmental risk assessment of pharmaceuticals with estrogenic properties.From1 Jan 2015 → 31 Dec 2018Funding: IWT personal funding - strategic basic research grants
Publications
1 - 10 of 107
- Comprehensive mapping of the AOP-Wiki database(2024)
Authors: Thomas Jaylet, Thibaut Coustillet, Nicola M. Smith, Barbara Viviani, Birgitte Lindeman, Lucia Vergauwen, Oddvar Myhre, Nurettin Yarar, Johanna M. Gostner, Pablo Monfort-Lanzas, et al.
Pages: 1 - 22 - Development of new approach methods for the identification and characterization of endocrine metabolic disruptors(2023)
Authors: Albert Braeuning, Patrick Balaguer, William Bourguet, Jordi Carreras-Puigvert, Katreece Feiertag, Jorke H. Kamstra, Dries Knapen, Dajana Lichtenstein, Philip Marx-Stoelting, Jonne Rietdijk, et al.
Pages: 1 - 7 - Chronic handling stress in zebrafish Danio rerio husbandry(2023)
Authors: Charlotte Philippe, Lucia Vergauwen, Kato Huyghe, Gudrun De Boeck, Dries Knapen
Pages: 367 - 377 - New approach methods to improve human health risk assessment of thyroid hormone system disruption – a PARC project(2023)
Authors: Louise Ramhøj, Marta Axelstad, Yoni Baert, Ana I. Cañas-Portilla, Frédéric Chalmel, Lars Dahmen, Antonio De La Vieja, Bertrand Evrard, Ann-Cathrin Haigis, Timo Hamers, et al.
Pages: 1 - 10 - Deiodinase inhibition impairs the formation of the three posterior swim bladder tissue layers during early embryonic development in zebrafish(2023)
Authors: Lucia Vergauwen, Ann-Cathrin Haigis, Brett R. Blackwell, Emma Stacy, Daniel L. Villeneuve, Dries Knapen
Pages: 1 - 11 - Leidraad ter bevordering van het welzijn van zebravissen in proefdierfaciliteiten(2023)
Authors: Charlotte Philippe, Lucia Vergauwen, Chris Van Ginneken, Gudrun De Boeck, Dries Knapen
Number of pages: 94 - Development of the integrated Fish Endocrine Disruptor Test (iFEDT) – part A(2023)
Authors: Pauline Pannetier, Lisa Gölz, Maria Teresa Pissarreira Mendes Fagundes, Susanne Knörr, Laura Behnstedt, Sara Coordes, Peter Matthiessen, Jane Ebsen Morthorst, Lucia Vergauwen, Dries Knapen, et al.
Pages: 1 - 13 - Development of the integrated fish endocrine disruptor test — part B(2023)
Authors: Lisa Gölz, Pauline Pannetier, Teresa Fagundes, Susanne Knörr, Laura Behnstedt, Sara Coordes, Peter Matthiessen, Jane Morthorst, Lucia Vergauwen, Dries Knapen, et al.
Pages: 1 - 16 - Cross-species applicability of an adverse outcome pathway network for thyroid hormone system disruption(2023)
Authors: Ann-Cathrin Haigis, Lucia Vergauwen, Carlie A. LaLone, Daniel L. Villeneuve, Jason M. O’Brien, Dries Knapen
Pages: 1 - 27 - Combined western diet and bisphenol A exposure induces an oxidative stress-based paraoxonase 1 response in larval zebrafish(2023)
Authors: Rik van den Boom, Lucia Vergauwen, Noortje Koedijk, Katyeny Manuela Da Silva, Adrian Covaci, Dries Knapen
Pages: 1 - 11