Researcher
Dries Knapen
- Research Expertise:Aquatic toxicology, zebrafish, adverse outcome pathways, stress physiology, systems biology, developmental biology, embryonic development, alternative testing approaches
- Keywords:ECOTOXICOLOGY, FISH ECOTOXICOLOGY, TOXICOLOGY, REPRODUCTIVE PHYSIOLOGY AND TOXICITY, ENVIRONMENTAL TOXICOLOGY, EMBRYOTOXICITY, Biology
- Disciplines:Environmental impact and risk assessment
- Research techniques:Zebrafish embryo test, zebrafish test, alternative in chemico and in vitro tests
- Users of research expertise:Toxicology, ecotoxicology
Affiliations
- Veterinary physiology and biochemistry (Research group)
Member
From1 Oct 2010 → Today - Systemic Physiological and Ecotoxicological Research (SPHERE) (Research group)
Member
From1 Oct 2003 → 30 Sep 2010
Projects
1 - 10 of 37
- Development of a mechanistic Integrated Approaches for Testing and Assessment (IATA) model for the identification of thyroid hormone system disrupting chemicals.From1 Nov 2023 → TodayFunding: FOD Public Health, Safety of the food chain and the Environment
- Partnership for the Assessment of Risks from Chemicals (PARC).From1 May 2022 → TodayFunding: HORIZON.2.1 - Health
- Vital crop growth through usage of microalgaebased biostimulants (VIGOROUS).From1 Oct 2021 → TodayFunding: FWO Strategic Basic Research (SBO)
- Thyroid hormone system disruption during early and late zebrafish embryo development.From1 Oct 2021 → TodayFunding: BOF - doctoral mandates
- Elucidating the pathogenicity of genetic variants of uncertain significance in Brugada syndrome patients by functional modelling in hiPSC-derived cardiomyocytes and zebrafish.From1 Nov 2020 → TodayFunding: FWO fellowships
- SPHERE LAB: An accredited body for ecotoxicological risk assessment.From1 Sep 2020 → 31 Aug 2021Funding: IOF - technology validation in real environment
- Development of a guidance document for improving zebrafish welfare in laboratory animal facilities.From1 Sep 2020 → 31 Jan 2023Funding: Department of Environment
- From exposome to effect assessment of contaminants in human and animal models (EXPOSOME).From1 Jan 2020 → TodayFunding: BOF - research organisations, Fund Recuperation Fiscal Exemption
- An integrated multi-purpose basic infrastructure for dynamic and sensitive metabolic profiling of cells and embryos.From1 Jan 2020 → 31 Dec 2021Funding: BOF - scientific equipment program
- Breaking down the wall between human health and environmental testing of endocrine disrupters: EndocRine Guideline Optimisation (ERGO).From1 Jan 2019 → TodayFunding: H2020-EU.3.1. - SOCIETAL CHALLENGES - Health, demographic change and wellbeing
Publications
41 - 50 of 107
- Evaluating complex mixtures in the zebrafish embryo by reconstituting field water samples(2017)
Authors: Ellen Michiels, Lucia Vergauwen, An Hagenaars, Erik Fransen, Stefan Van Dongen, Steven Van Cruchten, Lieven Bervoets, Dries Knapen
- Adverse outcome pathways(2017)
Authors: Mathieu Vinken, Dries Knapen, Lucia Vergauwen, Jan G. Hengstler, Michelle Angrish, Maurice Whelan
Pages: 3697 - 3707 - Antioxidants reduce reactive oxygen species but not embryotoxicity in the metabolic Danio rerio test (mDarT)(2017)
Authors: Casper Pype, Evy Verbueken, Moayad Saad, Chloe Bars, Chris Van Ginneken, Dries Knapen, Steven Van Cruchten
Pages: 62 - 73 - Advancing the adverse outcome pathway framework(2017)
Authors: Carlie A. LaLone, Gerald T. Ankley, Scott E. Belanger, Michelle R. Embry, Geoff Hodges, Dries Knapen, Sharon Munn, Edward J. Perkins, Murray A. Rudd, Daniel L. Villeneuve, et al.
Pages: 1411 - 1421 - The role of omics in the application of adverse outcome pathways for chemical risk assessment(2017)
Authors: Erica K. Brockmeier, Geoff Hodges, Thomas H. Hutchinson, Emma Butler, Markus Hecker, Knut Erik Tollefsen, Natalia Garcia-Reyero, Peter Kille, Doerthe Becker, Kevin Chipman, et al.
Pages: 252 - 262 - Impaired swim bladder inflation in early life stage fathead minnows exposed to a deiodinase inhibitor, iopanoic acid(2017)
Authors: Jenna E. Cavallin, Gerald T. Ankley, Brett R. Blackwell, Chad A. Blanksma, Kellie A. Fay, Kathleen M. Jensen, Michael D. Kahl, Dries Knapen, Patricia A. Kosian, Shane T. Poole, et al.
Pages: 2942 - 2952 - Prioritization of contaminated watercourses using an integrated biomarker approach in caged carp(2016)
Authors: Sébastjen Schoenaers, Lucia Vergauwen, An Hagenaars, Lynn Vanhaecke, Hamada Abd Elgawad, Han Asard, Adrian Covaci, Lieven Bervoets, Dries Knapen
Pages: 129 - 139 - Deiodinase knockdown affects zebrafish eye development at the level of gene expression, morphology and function(2016)
Authors: Anne M. Houbrechts, Lucia Vergauwen, Enise Bagci, Jolien Van Houcke, Marjolein Heijlen, Bernard Kulemeka, David R. Hyde, Dries Knapen, Veerle M. Darras
Pages: 81 - 93 - Impaired anterior swim bladder inflation following exposure to the thyroid peroxidase inhibitor 2-mercaptobenzothiazole part 1(2016)
Authors: Krysta R. Nelson, Anthony L. Schroeder, Gerald T. Ankley, Brett R. Blackwell, Chad Blanksma, Sigmund J. Degitz, Kevin M. Flynn, Kathleen M. Jensen, Rodney D. Johnson, Michael D. Kahl, et al.
Pages: 192 - 203 - Microarray-based annotation of the gut transcriptome of the migratory locust, $\mathit{Locusta}$ $\mathit{migratoria}$(2016)
Authors: J. Spit, L. Badisco, Lucia Vergauwen, Dries Knapen, J. Vanden Broeck
Pages: 745 - 756