Researcher
Dries Knapen
- Research Expertise:Aquatic toxicology, zebrafish, adverse outcome pathways, stress physiology, systems biology, developmental biology, embryonic development, alternative testing approaches
- Keywords:ECOTOXICOLOGY, FISH ECOTOXICOLOGY, TOXICOLOGY, REPRODUCTIVE PHYSIOLOGY AND TOXICITY, ENVIRONMENTAL TOXICOLOGY, EMBRYOTOXICITY, Biology
- Disciplines:Environmental impact and risk assessment
- Research techniques:Zebrafish embryo test, zebrafish test, alternative in chemico and in vitro tests
- Users of research expertise:Toxicology, ecotoxicology
Affiliations
- Veterinary physiology and biochemistry (Research group)
Member
From1 Oct 2010 → Today - Systemic Physiological and Ecotoxicological Research (SPHERE) (Research group)
Member
From1 Oct 2003 → 30 Sep 2010
Projects
1 - 10 of 37
- Development of a mechanistic Integrated Approaches for Testing and Assessment (IATA) model for the identification of thyroid hormone system disrupting chemicals.From1 Nov 2023 → TodayFunding: FOD Public Health, Safety of the food chain and the Environment
- Partnership for the Assessment of Risks from Chemicals (PARC).From1 May 2022 → TodayFunding: HORIZON.2.1 - Health
- Vital crop growth through usage of microalgaebased biostimulants (VIGOROUS).From1 Oct 2021 → TodayFunding: FWO Strategic Basic Research (SBO)
- Thyroid hormone system disruption during early and late zebrafish embryo development.From1 Oct 2021 → TodayFunding: BOF - doctoral mandates
- Elucidating the pathogenicity of genetic variants of uncertain significance in Brugada syndrome patients by functional modelling in hiPSC-derived cardiomyocytes and zebrafish.From1 Nov 2020 → TodayFunding: FWO fellowships
- SPHERE LAB: An accredited body for ecotoxicological risk assessment.From1 Sep 2020 → 31 Aug 2021Funding: IOF - technology validation in real environment
- Development of a guidance document for improving zebrafish welfare in laboratory animal facilities.From1 Sep 2020 → 31 Jan 2023Funding: Department of Environment
- From exposome to effect assessment of contaminants in human and animal models (EXPOSOME).From1 Jan 2020 → TodayFunding: BOF - research organisations, Fund Recuperation Fiscal Exemption
- An integrated multi-purpose basic infrastructure for dynamic and sensitive metabolic profiling of cells and embryos.From1 Jan 2020 → 31 Dec 2021Funding: BOF - scientific equipment program
- Breaking down the wall between human health and environmental testing of endocrine disrupters: EndocRine Guideline Optimisation (ERGO).From1 Jan 2019 → TodayFunding: H2020-EU.3.1. - SOCIETAL CHALLENGES - Health, demographic change and wellbeing
Publications
1 - 10 of 107
- Comprehensive mapping of the AOP-Wiki database(2024)
Authors: Thomas Jaylet, Thibaut Coustillet, Nicola M. Smith, Barbara Viviani, Birgitte Lindeman, Lucia Vergauwen, Oddvar Myhre, Nurettin Yarar, Johanna M. Gostner, Pablo Monfort-Lanzas, et al.
Pages: 1 - 22 - Development of new approach methods for the identification and characterization of endocrine metabolic disruptors(2023)
Authors: Albert Braeuning, Patrick Balaguer, William Bourguet, Jordi Carreras-Puigvert, Katreece Feiertag, Jorke H. Kamstra, Dries Knapen, Dajana Lichtenstein, Philip Marx-Stoelting, Jonne Rietdijk, et al.
Pages: 1 - 7 - Chronic handling stress in zebrafish Danio rerio husbandry(2023)
Authors: Charlotte Philippe, Lucia Vergauwen, Kato Huyghe, Gudrun De Boeck, Dries Knapen
Pages: 367 - 377 - New approach methods to improve human health risk assessment of thyroid hormone system disruption – a PARC project(2023)
Authors: Louise Ramhøj, Marta Axelstad, Yoni Baert, Ana I. Cañas-Portilla, Frédéric Chalmel, Lars Dahmen, Antonio De La Vieja, Bertrand Evrard, Ann-Cathrin Haigis, Timo Hamers, et al.
Pages: 1 - 10 - Deiodinase inhibition impairs the formation of the three posterior swim bladder tissue layers during early embryonic development in zebrafish(2023)
Authors: Lucia Vergauwen, Ann-Cathrin Haigis, Brett R. Blackwell, Emma Stacy, Daniel L. Villeneuve, Dries Knapen
Pages: 1 - 11 - Leidraad ter bevordering van het welzijn van zebravissen in proefdierfaciliteiten(2023)
Authors: Charlotte Philippe, Lucia Vergauwen, Chris Van Ginneken, Gudrun De Boeck, Dries Knapen
Number of pages: 94 - Development of the integrated Fish Endocrine Disruptor Test (iFEDT) – part A(2023)
Authors: Pauline Pannetier, Lisa Gölz, Maria Teresa Pissarreira Mendes Fagundes, Susanne Knörr, Laura Behnstedt, Sara Coordes, Peter Matthiessen, Jane Ebsen Morthorst, Lucia Vergauwen, Dries Knapen, et al.
Pages: 1 - 13 - Development of the integrated fish endocrine disruptor test — part B(2023)
Authors: Lisa Gölz, Pauline Pannetier, Teresa Fagundes, Susanne Knörr, Laura Behnstedt, Sara Coordes, Peter Matthiessen, Jane Morthorst, Lucia Vergauwen, Dries Knapen, et al.
Pages: 1 - 16 - Cross-species applicability of an adverse outcome pathway network for thyroid hormone system disruption(2023)
Authors: Ann-Cathrin Haigis, Lucia Vergauwen, Carlie A. LaLone, Daniel L. Villeneuve, Jason M. O’Brien, Dries Knapen
Pages: 1 - 27 - Combined western diet and bisphenol A exposure induces an oxidative stress-based paraoxonase 1 response in larval zebrafish(2023)
Authors: Rik van den Boom, Lucia Vergauwen, Noortje Koedijk, Katyeny Manuela Da Silva, Adrian Covaci, Dries Knapen
Pages: 1 - 11