Researcher
Catherine Verfaillie
- Disciplines:Genetics, Systems biology, Molecular and cell biology
Affiliations
- Stem Cell and Developmental Biology (Division)
Member
From1 Apr 2013 → 30 Sep 2022
Infrastructure
1 - 1 of 1
- Platform for Next Generation Screening in Quantitative Biology & Drug Discovery (Consortium coordinator)
Projects
1 - 10 of 95
- Business development of a drug screening Spin-off company based on 2D & 3D human iPSC-derived liver cell models for NASH & (i)DILI.From1 Aug 2021 → 31 Jan 2022Funding: IOF - mandates
- RISK assessment of chemicals integrating HUman centric Next generation Testing strategies promoting the 3RsFrom1 Jun 2021 → TodayFunding: H2020 - Health, demographic change and wellbeing
- Robotized Human Liver-Mimic 3D Model Platform for Efficient NAFLD and DILI Compound ScreeningFrom1 Jan 2021 → 31 Dec 2022Funding: IOF - technology validation in lab
- Advanced 3D Complex Tissues BioAssembly Platform for Precision Disease Modeling, Drug Discovery and Regenerative Medicine (3D-BioBOT)From1 Jan 2021 → 31 Dec 2022Funding: BOF - scientific equipment program
- In vitro functional formation of liver sinusoidal endothelial cells in 3D culture system.From1 Oct 2020 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- iPSC-based parenchymal and sinusoidal liver cell mimics for DILI and NAFLD studies (iPSC-LiMic)From1 Oct 2020 → TodayFunding: FWO Strategic Basic Research (SBO)
- Drug discovery for Parkinson’s disease using a translational screening platformFrom1 Oct 2020 → 31 Mar 2024Funding: IOF - technology validation in lab
- OrganID: Organ-derived complex 2D/3D cultures in human diseaseFrom1 Oct 2020 → TodayFunding: FWO Strategic Basic Research (SBO)
- Proof of concept: immunotherapy in glioblastoma multiforme.From21 Sep 2020 → TodayFunding: FWO fellowships
- 3D-PADchip: Engineering 3D Perfusable human "Alzheimer's Disease (AD)-On-Chip ModelFrom28 Aug 2020 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
Publications
1 - 10 of 375
- Xenografted human microglia display diverse transcriptomic states in response to Alzheimer's disease-related amyloid-β pathology.(2024)
Authors: Sriram Balusu, Catherine Verfaillie, Bart De Strooper
- Glycolytic state of aortic endothelium favors hematopoietic transition during the emergence of definitive hematopoiesis.(2024)
Authors: Catherine Verfaillie
Pages: eadh8478 - Spatially Self-Organized Three-Dimensional Neural Concentroid as a Novel Reductionist Humanized Model to Study Neurovascular Development(2024)
Authors: Yoke Chin Chai, San Kit To, Yingli Zhu, Ben van der Veer, Vincent Pasque, Catherine Verfaillie
- Osmolar Modulation Drives Reversible Cell Cycle Exit and Human Pluripotent Cell Differentiation via NF-κВ and WNT Signaling(2024)
Authors: Jonathan Chui, Aneta Malesa, Paraskevi ATHANASOULI, Joris Vriens, Kian Koh, Catherine Verfaillie, Frederic Lluis Vinas
- Robotics-Driven Manufacturing of Cartilaginous Microtissues for Skeletal Tissue Engineering Applications(2024)
Authors: Isaak Decoene, Gabriele Nasello, Catherine Verfaillie, Liesbet Geris, Frank Luyten, Ioannis Papantoniou
Pages: 278 - 292 - Automated Generation of hiPSC-Derived Hepatic Progeny by Cost-Efficient Compounds(2023)
Authors: Kristof De Vos, Teresa Izuel Idoype, Pieter Annaert, Frederic Lluis Vinas, Catherine Verfaillie
Pages: 1076 - 1088 - Editorial: New insights of immune cells in cardiovascular and metabolic disorders(2023)
Authors: Catherine Verfaillie
- Engineering Neurovascular Organoids and Morphogen Gradients with 3D Printed Microfluidic Chips(2023)
Authors: Idris Salmon, Adrian Ranga, Catherine Verfaillie
- APEX1 Nuclease and Redox Functions are Both Essential for Adult Mouse Hematopoietic Stem and Progenitor Cells(2023)
Authors: Samantha Zaunz, Lukas Lauwereins, Kim De Keersmaecker, Catherine Verfaillie
Pages: 2052 - 2072 - From methylation to myelination: epigenomic and transcriptomic profiling of chronic inactive demyelinated multiple sclerosis lesions(2023)
Authors: Catherine Verfaillie
Pages: 283 - 299
Patents
1 - 10 of 10
- Methods for differentiating cells into hepatic stellate cells (Inventor)
- Hydrogels for cell culture (Inventor)
- Nek6 inhibition to treat als and ftd (Inventor)
- Spheroidal self-assembled peptide hydrogels comprising cells (Inventor)
- Methods for differentiating cells into hepatic stellate cells (Inventor)
- Cell culture media for differentiation of stem cells into hepatocytes (Inventor)
- Methods for identifying activators and suppressors (Inventor)
- Stem cell aggregates and methods for making and using (Inventor)
- Cell therapy for myelodysplastic syndromes (Inventor)
- Optimized methods for differentiation of cells into cells with hepatocyte and hepatocyte progenitor phenotypes, cells produced by the methods, and methods for using the cells (Inventor)