Researcher
Catherine Verfaillie
- Disciplines:Genetics, Systems biology, Molecular and cell biology
Affiliations
- Stem Cell and Developmental Biology (Division)
Member
From1 Apr 2013 → 30 Sep 2022
Infrastructure
1 - 1 of 1
- Platform for Next Generation Screening in Quantitative Biology & Drug Discovery (Consortium coordinator)
Projects
1 - 10 of 95
- Business development of a drug screening Spin-off company based on 2D & 3D human iPSC-derived liver cell models for NASH & (i)DILI.From1 Aug 2021 → 31 Jan 2022Funding: IOF - mandates
- RISK assessment of chemicals integrating HUman centric Next generation Testing strategies promoting the 3RsFrom1 Jun 2021 → TodayFunding: H2020 - Health, demographic change and wellbeing
- Robotized Human Liver-Mimic 3D Model Platform for Efficient NAFLD and DILI Compound ScreeningFrom1 Jan 2021 → 31 Dec 2022Funding: IOF - technology validation in lab
- Advanced 3D Complex Tissues BioAssembly Platform for Precision Disease Modeling, Drug Discovery and Regenerative Medicine (3D-BioBOT)From1 Jan 2021 → 31 Dec 2022Funding: BOF - scientific equipment program
- In vitro functional formation of liver sinusoidal endothelial cells in 3D culture system.From1 Oct 2020 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- iPSC-based parenchymal and sinusoidal liver cell mimics for DILI and NAFLD studies (iPSC-LiMic)From1 Oct 2020 → TodayFunding: FWO Strategic Basic Research (SBO)
- Drug discovery for Parkinson’s disease using a translational screening platformFrom1 Oct 2020 → 31 Mar 2024Funding: IOF - technology validation in lab
- OrganID: Organ-derived complex 2D/3D cultures in human diseaseFrom1 Oct 2020 → TodayFunding: FWO Strategic Basic Research (SBO)
- Proof of concept: immunotherapy in glioblastoma multiforme.From21 Sep 2020 → TodayFunding: FWO fellowships
- 3D-PADchip: Engineering 3D Perfusable human "Alzheimer's Disease (AD)-On-Chip ModelFrom28 Aug 2020 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
Publications
31 - 40 of 375
- TOWARDS ROBOTICS-DRIVEN MANUFACTURING OF SPHEROID-BASED SKELETAL IMPLANTS(2022)
Authors: Isaak Decoene, Catherine Verfaillie, Liesbet Geris, Ioannis Papantoniou
Pages: S422 - S422 - Organoid and microfluidics-based platforms for drug screening in COVID-19(2022)
Authors: Roya Ramezankhani, Yoke Chin Chai, Catherine Verfaillie
Pages: 1062 - 1076 - Investigating the role of mutant TDP-43-ALS using human iPSC-derived motor neurons(2022)
Authors: Raheem Fazal, Philip Van Damme, Ludo Van Den Bosch, Catherine Verfaillie
- A Novel UPLC-MS Metabolomic Analysis-Based Strategy to Monitor the Course and Extent of iPSC Differentiation to Hepatocytes(2022)
Authors: Manoj Kumar Gautam, Tine Tricot, Ruben Boon, Burak Toprakhisar, Catherine Verfaillie
Pages: 702 - 712 - iPSC-derived cortical neurons to study sporadic Alzheimer disease: A transcriptome comparison with post-mortem brain samples(2022)
Authors: Catherine Verfaillie
Pages: 89 - 99 - Human iPSC model reveals a central role for NOX4 and oxidative stress in Duchenne cardiomyopathy(2022)
Authors: Robin Duelen, Domiziana Costamagna, Guillaume Gilbert, Liesbeth De Waele, Nathalie Goemans, Kaat Desloovere, Catherine Verfaillie, Karin Sipido, Gunnar Buyse, Maurilio Sampaolesi
Pages: 352 - 368 - Metabolically Improved Stem Cell Derived Hepatocyte-Like Cells Support HBV Life Cycle and Are a Promising Tool for HBV Studies and Antiviral Drug Screenings(2022)
Authors: Tine Tricot, Hendrik Jan Thibaut, Kayvan Abbasi, Manoj Kumar Gautam, Johan Neyts, Catherine Verfaillie
- Current Status and Challenges of Human Induced Pluripotent Stem Cell-Derived Liver Models in Drug Discovery(2022)
Authors: Tine Tricot, Catherine Verfaillie, Manoj Kumar Gautam
- ROLE OF OUTSIDE-IN INTEGRIN SIGNALING IN HEMATOPOIETIC DEVELOPMENT OF MOUSE EMBRYO(2022)
Authors: Catherine Verfaillie
Pages: S62 - S62 - HiPSC-Derived Hepatocyte-like Cells Can Be Used as a Model for Transcriptomics-Based Study of Chemical Toxicity(2022)
Authors: Sreya Ghosh, Tine Tricot, Manoj Kumar Gautam, FatemehArefeh Nami, Catherine Verfaillie
Patents
1 - 10 of 10
- Methods for differentiating cells into hepatic stellate cells (Inventor)
- Hydrogels for cell culture (Inventor)
- Nek6 inhibition to treat als and ftd (Inventor)
- Spheroidal self-assembled peptide hydrogels comprising cells (Inventor)
- Methods for differentiating cells into hepatic stellate cells (Inventor)
- Cell culture media for differentiation of stem cells into hepatocytes (Inventor)
- Methods for identifying activators and suppressors (Inventor)
- Stem cell aggregates and methods for making and using (Inventor)
- Cell therapy for myelodysplastic syndromes (Inventor)
- Optimized methods for differentiation of cells into cells with hepatocyte and hepatocyte progenitor phenotypes, cells produced by the methods, and methods for using the cells (Inventor)