Organisation
Laboratory of Computational Biology (VIB-KU Leuven)
Division
Research in the Laboratory of Computational Biology is focusing on gene and genome regulation, with applications in Drosophila and cancer, and on integrative genomics, developing computational methods for genomic data integration and analysis of next-generation sequence data.
Projects
51 - 60 of 64
- Classification of enhancer divergence in Drosophila speciesFrom1 Jan 2013 → 31 Dec 2016Funding: FWO research project (including WEAVE projects)
- Identification of coding and non-coding cancer drivers from whole-genome re-sequencing data using gene regulatory network analysis.From1 Oct 2012 → 23 Feb 2018Funding: IWT personal funding - strategic basic research grants
- PACBIO.From26 Apr 2012 → 1 Nov 2018Funding: Hercules - Large scale research infrastructure
- Discovery and prioritization of gene regulatory modules driving oncogenesis.From1 Oct 2011 → 30 Sep 2014Funding: FWO fellowships
- Identifying functional transcriptional targets by next-generation sequencing.From1 Aug 2011 → 31 Mar 2016Funding: Private funding of national origin - undefined, FWO fellowships
- From genes to circuits: the evolution of species-specific communication in Drosophila.From1 Jun 2011 → 31 May 2015Funding: Other international institutions, not mentioned elsewhere
- ChIP-STaR: A ChIP-Seq-based targetome reporter assay for the genome-wide identification of functional target genes of cancer-related transcription factors.From1 Jan 2011 → 31 Dec 2012Funding: Other federal scientific institutions
- From individual cancer genes to integrated cancer pathways in childhood cancer.From1 Jan 2011 → 31 Dec 2014Funding: FWO research project (including WEAVE projects)
- Deciphering gene regulatory networks and cis-regulatory codes in Drosophila through a combination of genetic perturbations, digital gene expression, and bioinformatics.From1 Jan 2011 → 31 Dec 2014Funding: FWO research project (including WEAVE projects)
- SymBioSys: from variome to phenome.From1 Nov 2010 → 31 Oct 2018Funding: BOF - Concerted Research Project from 1994
Publications
1 - 10 of 177
- Identification of Circulating Fibrocytes and Dendritic Derivatives in Corneal Endothelium of Patients With Fuchs' Dystrophy(2017)
Authors: An-Katrien De Roo, Jasper Wouters, Olivier Govaere, Beatrijs Foets, Joost van den Oord
Pages: 670 - 681 - CNKSR1 gene defect can cause syndromic autosomal recessive intellectual disability.(2018)
Authors: Ibrahim Ihsan Taskiran
Pages: 691 - 699 - Recurrent rearrangements of FOS and FOSB define osteoblastoma(2018)
Authors: Annelien Verfaillie, Jonas Demeulemeester, Peter Van Loo
- Gene losses in the common vampire bat illuminate molecular adaptations to blood feeding(2022)
Authors: Nikolai Hecker
- iRegulon: From a Gene List to a Gene Regulatory Network Using Large Motif and Track Collections(2014)
Authors: Annelien Verfaillie, Hana Imrichova, Bram Van de Sande, Laura Standaert, Marina Naval Sanchez, Delphine Potier, Dmitry Svetlichnyy, Zeynep Kalender Atak, Mark Fiers, Chris Marine, et al.
- Male-Specific Fruitless Isoforms Target Neurodevelopmental Genes to Specify a Sexually Dimorphic Nervous System(2014)
Authors: Bram Van de Sande, Stein Aerts
Pages: 229 - 241 - Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state(2015)
Authors: Annelien Verfaillie, Hana Imrichova, Zeynep Kalender Atak, Michael Dewaele, Valerie Christiaens, Dmitry Svetlichnyy, Flavie Luciani, Laura Van den Mooter, Sofie Claerhout, Mark Fiers, et al.
- EXPLORING THE CODE OF LIFE: FROM DECODING TO DESIGNING CELL TYPE-SPECIFIC ENHANCERS WITH DEEP LEARNING(2023)
Authors: Ibrahim Ihsan Taskiran, Stein Aerts
- Adult interfollicular tumour-initiating cells are reprogrammed into an embryonic hair follicle progenitor-like fate during basal cell carcinoma initiation(2012)
Authors: Bram Van de Sande, Stein Aerts
Pages: 1282 - 1294 - Sequencing the regulatory genome(2008)
Authors: Stein Aerts