Differential expression of alpha B-crystallin and evidence of its role as a mediator of matrix gene expression in osteoarthritis Universiteit Gent
Objective. Alpha B-crystallin belongs to the family of small heat-shock proteins (HSPs). The role of this protein family in chondrocytes is not well understood. The present study was undertaken to investigate expression levels of alpha B-crystallin in chondrocytes isolated from healthy subjects and patients with osteoarthritis (OA), and to explore the functional role of this potentially interesting protein in chondrocyte metabolism. Methods. ...