Publicaties
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Identification of a novel mechanism of blood-brain communication during peripheral inflammation via choroid plexus-derived extracellular vesicles Universiteit Gent
Protein modification and maintenance systems as biomarkers of ageing Universiteit Gent
Plasma N-glycome signature of Down syndrome Universiteit Gent
N-Glycomic changes in serum proteins in type 2 diabetes mellitus correlate with complications and with metabolic syndrome parameters Universiteit Gent
Background: Glycosylation, i.e the enzymatic addition of oligosaccharides (or glycans) to proteins and lipids, known as glycosylation, is one of the most common co-/posttranslational modifications of proteins. Many important biological roles of glycoproteins are modulated by N-linked oligosaccharides. As glucose levels can affect the pathways leading to glycosylation of proteins, we investigated whether metabolic syndrome (MS) and type 2 ...
Determining differentially expressed miRNAs and validating miRNA-target relationships using the SPRET/Ei mouse strain Universiteit Gent
N-glycome profile levels relate to silent brain infarcts in a cohort of hypertensives Universiteit Gent
Background: Silent brain infarcts (SBIs) are highly prevalent in the aged population and relate to the occurrence of further stroke and dementia. Serum N-glycome levels have been previously associated with aging and they might be related as well to the presence of SBIs and age-related white matter hyperintensities. Methods and Results: We determined the serum N-glycome profile in a cohort study comprising 972 subjects and evaluated the ...