Onderzoeker
Ruben Boon
- Disciplines:Genetica, Systeembiologie, Moleculaire en celbiologie, Morfologische wetenschappen, Oncologie
Affiliaties
- Laboratorium voor Functionele Epigenetica (Afdeling)
Lid
Vanaf1 sep 2021 → 31 jan 2022 - Stamcel- en Ontwikkelingsbiologie (Afdeling)
Lid
Vanaf1 apr 2013 → 31 dec 2018
Projecten
1 - 1 of 1
- Metabolomics van stamceldifferentiatie.Vanaf13 aug 2012 → 13 dec 2017Financiering: IWT persoonsgebonden financ. - strategische onderzoeksbeurzen
Publicaties
11 - 20 van 34
- Human stem cell-derived monocytes and microglia-like cells reveal impaired amyloid plaque clearance upon heterozygous or homozygous loss of TREM2(2019)
Auteurs: Christel Claes, Johanna Van Den Daele, Ruben Boon, Mark Fiers, FatemehArefeh Nami, Bart De Strooper, Catherine Verfaillie
Pagina's: 453 - 464 - Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity(2019)
Auteurs: dorien Broekaert, Ali Talebi, Jonas Dehairs, Matteo Rossi, Gianmarco Rinaldi, Ruben Boon, Catherine Verfaillie, Rita Derua, Sebastian Munck, Johan Swinnen, et al.
Pagina's: 403 - 406 - Generation of Hepatic Stellate Cells from Human Pluripotent Stem Cells Enables In Vitro Modeling of Liver Fibrosis(2018)
Auteurs: Ruben Boon, Catherine Verfaillie
Pagina's: 101 - + - SOX10 Single Transcription Factor-Based Fast and Efficient Generation of Oligodendrocytes from Human Pluripotent Stem Cells(2018)
Auteurs: Manoj Kumar Gautam, Ruben Boon, Esther Wolfs, Catherine Verfaillie
Pagina's: 655 - 672 - Efficient Recombinase-Mediated Cassette Exchange in hPSCs to Study the Hepatocyte Lineage Reveals AAVS1 Locus-Mediated Transgene Inhibition(2018)
Auteurs: Laura Ordovas Vidal, Ruben Boon, Elena Pistoni, Yemiao Chen, Esther Wolfs, Wenting Guo, Rangarajan Sambathkumar, Sylwia Bobis-Wozowicz, Nicky Helsen, Jolien Vanhove, et al.
Pagina's: 673 - Generation of functional liver cells through genome engineering and recreation of the cellular microenvironment(2017)
Auteurs: Ruben Boon, Catherine Verfaillie, Peter Carmeliet
- HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients(2017)
Auteurs: Wenting Guo, Laura Fumagalli, Tijs Vandoorne, Ruben Boon, Samie PATEL, Tine Tricot, Veronick Benoy, Jolien Steyaert, Werend Boesmans, Pieter Vanden Berghe, et al.
Pagina's: 861 - Dual loss of succinate dehydrogenase (SDH) and complex I activity is necessary to recapitulate the metabolic phenotype of SDH mutant tumors(2017)
Auteurs: Gianmarco Rinaldi, Ruben Boon, Kristine Metzger, Karin Voordeckers, Patrik Verstreken, David Cassiman, Pieter Vermeersch, Catherine Verfaillie, Sarah-Maria Fendt
Pagina's: 187 - 197 - Proline metabolism supports metastasis formation and could be inhibited to selectively target metastasizing cancer cells(2017)
Auteurs: Ilaria Elia, dorien Broekaert, Ruben Boon, Catherine Verfaillie, Sarah-Maria Fendt
Pagina's: 15267 - Dynamic regulation of EZH2 from HPSc to hepatocyte-like cell fate(2017)
Auteurs: Elena Pistoni, Nicky Helsen, Jolien Vanhove, Ruben Boon, Zhuofei Xu, Laura Ordovas Vidal, Catherine Verfaillie
Pagina's: 0186884
Patenten
1 - 5 van 5
- Methods for differentiating cells into hepatic stellate cells (Inventor)
- Methods for differentiating cells into hepatic stellate cells (Inventor)
- Cell culture media for differentiation of stem cells into hepatocytes (Inventor)
- Cell culture media for differentiation of stem cells into hepatocytes (Inventor)
- Methods for differentiating cells into hepatic stellate cells (Inventor)