Onderzoeker
Mieke Nys
- Disciplines:Neurowetenschappen, Biologische en fysiologische psychologie, Cognitieve wetenschappen en intelligente systemen, Ontwikkelingspsychologie en veroudering
Affiliaties
- Laboratorium voor Structurele Neurobiologie (Afdeling)
Lid
Vanaf19 jul 2010 → Heden
Projecten
1 - 1 of 1
- Een breed-spectrum antigif tegen giftige slangenbeten gebaseerd op ontwikkeling van nicotine acetylcholine receptoren en afgeleiden.Vanaf1 nov 2021 → HedenFinanciering: FWO junior postdoctoraal mandaat
Publicaties
1 - 10 van 13
- An in vitro assay to investigate venom neurotoxin activity on muscle-type nicotinic acetylcholine receptor activation and for the discovery of toxin-inhibitory molecules(2023)
Auteurs: Mieke Nys, Chris Ulens
- Exploiting the intrinsic misfolding propensity of the KRAS oncoprotein(2023)
Auteurs: Kobe Janssen, Filip Claes, Bert Houben, Mieke Nys, Laleh Khodaparast, Ladan Khodaparast, Nikolaos Louros, Rob van der Kant, Katerina Konstantoulea, Joost Schymkowitz, et al.
- The molecular mechanism of snake short-chain α-neurotoxin binding to muscle-type nicotinic acetylcholine receptors(2022)
Auteurs: Mieke Nys, Chris Ulens
- The structural basis for an on-off switch controlling Gβγ-mediated inhibition of TRPM3 channels(2020)
Auteurs: Mieke Nys, Nikolaos Louros, Rodrigo Gallardo, Valentina Zorzini, Tassos Economou, Frederic Rousseau, Joost Schymkowitz, Chris Ulens
Pagina's: 29090 - 29100 - Structure-Guided Exploration of SDS22 Interactions with Protein Phosphatase PP1 and the Splicing Factor BCLAF1(2019)
Auteurs: Mieke Nys, Rita Derua, Monique Beullens, Chris Ulens, Luc Van Meervelt, Mathieu Bollen
Pagina's: 507 - + - Functional and Biochemical Characterization of Alvinella pompejana Cys-Loop Receptor Homologues(2016)
Auteurs: Eveline Wijckmans, Mieke Nys, Chris Ulens
- Allosteric binding site in a Cys-loop receptor ligand-binding domain unveiled in the crystal structure of ELIC in complex with chlorpromazine(2016)
Auteurs: Mieke Nys, Eveline Wijckmans, Radovan Spurny, Steve Peigneur, Jan Tytgat, Chris Ulens
Pagina's: E6696 - E6703 - The Crystal Structure of ELIC in Complex with Chlorpromazine Unexpectedly Unveils an Allosteric Binding Site in the Ligand-Binding Domain(2016)
Auteurs: Mieke Nys, Ana Farinha, Eveline Wijckmans, Marijke Brams, Ozge Yoluk, Magnus Andersson, Erik Lindahl, Chris Ulens
Pagina's: 457 - Functional and Biochemical Characterization of Alvinella Pompejana Cys-Loop Receptor Homologues(2016)
Auteurs: Eveline Wijckmans, Mieke Nys, Sarah Debaveye, Marijke Brams, Els Pardon, Daniel Bertrand, Jan Steyaert, Chris Ulens
Pagina's: 602 - Structure of the SthK Carboxy-Terminal Region Reveals a Gating Mechanism for Cyclic Nucleotide-Modulated Ion Channels(2015)
Auteurs: Divya Kesters, Mieke Nys, Eveline Wijckmans, Radovan Spurny, Thomas Voets, Jan Tytgat, Chris Ulens