Researcher
Mieke Nys
- Disciplines:Neurosciences, Biological and physiological psychology, Cognitive science and intelligent systems, Developmental psychology and ageing
Affiliations
- Laboratory of Structural Neurobiology (Division)
Member
From19 Jul 2010 → Today
Projects
1 - 1 of 1
- A broad-spectrum antidote against venomous snakebites based on engineering of nicotinic acetylcholine receptors and derivatives.From1 Nov 2021 → 1 Jun 2024Funding: FWO junior postdoctoral fellowship
Publications
1 - 10 of 11
- An in vitro assay to investigate venom neurotoxin activity on muscle-type nicotinic acetylcholine receptor activation and for the discovery of toxin-inhibitory molecules(2023)
Authors: Mieke Nys, Chris Ulens
- Exploiting the intrinsic misfolding propensity of the KRAS oncoprotein(2023)
Authors: Kobe Janssen, Filip Claes, Bert Houben, Mieke Nys, Laleh Khodaparast, Ladan Khodaparast, Nikolaos Louros, Rob van der Kant, Katerina Konstantoulea, Joost Schymkowitz, et al.
- The molecular mechanism of snake short-chain α-neurotoxin binding to muscle-type nicotinic acetylcholine receptors(2022)
Authors: Mieke Nys, Chris Ulens
- The structural basis for an on-off switch controlling Gβγ-mediated inhibition of TRPM3 channels(2020)
Authors: Mieke Nys, Nikolaos Louros, Rodrigo Gallardo, Valentina Zorzini, Tassos Economou, Frederic Rousseau, Joost Schymkowitz, Chris Ulens
Pages: 29090 - 29100 - Structure-Guided Exploration of SDS22 Interactions with Protein Phosphatase PP1 and the Splicing Factor BCLAF1(2019)
Authors: Mieke Nys, Rita Derua, Monique Beullens, Chris Ulens, Luc Van Meervelt, Mathieu Bollen
Pages: 507 - + - BIOCHEMISCHE KARAKTERISATIE VAN PENTAMERE LIGAND-GEACTIVEERDE IONENKANALEN(2016)
Authors: Mieke Nys, Chris Ulens
Number of pages: 152 - Functional and Biochemical Characterization of Alvinella pompejana Cys-Loop Receptor Homologues(2016)
Authors: Eveline Wijckmans, Mieke Nys, Chris Ulens
- Allosteric binding site in a Cys-loop receptor ligand-binding domain unveiled in the crystal structure of ELIC in complex with chlorpromazine(2016)
Authors: Mieke Nys, Eveline Wijckmans, Radovan Spurny, Steve Peigneur, Jan Tytgat, Chris Ulens
Pages: E6696 - E6703 - Structure of the SthK Carboxy-Terminal Region Reveals a Gating Mechanism for Cyclic Nucleotide-Modulated Ion Channels(2015)
Authors: Divya Kesters, Mieke Nys, Eveline Wijckmans, Radovan Spurny, Thomas Voets, Jan Tytgat, Chris Ulens
- Structural insights into Cys-loop receptor function and ligand recognition(2013)
Authors: Mieke Nys, Divya Kesters, Chris Ulens
Pages: 1042 - 1053