Projects
The role of GLucose homeostasis and metabOlomics in pregnancy outcomes afteR barIAtric surgery: the GLORIA study. KU Leuven
Glucose homeostasis, metabolomics and pregnancy outcomes after bariatric surgery: the GLORIA study The prevalence of obesity and metabolic syndrome is increasing at an alarming rate worldwide. Obesity in women is associated with infertility and miscarriages. During pregnancy, obesity is associated with increased risk of gestational diabetes mellitus (GDM), preeclampsia, macrosomia and caesarean delivery. For women with a body mass index (BMI) ...
Post-mortem tissue biobanking to illuminate end-stage ovarian cancer disease (ATLASOvCANCER) KU Leuven
Serous ovarian cancer, consisting of 2 distinct types (i.e. low-grade, LGSOC, and high-grade, HGSOC, cancers), is the most lethal gynecological malignancy. Patients are typically diagnosed in advanced stages, when the cancer has already spread (metastasized) from the primary site to numerous sites in the belly. Surgery and chemotherapy remain the mainstream treatments. Yet, most patients develop resistance to treatment and virtually all ...
ORDECA – ORganoid Drug screening for Endometrial CAncerIdentifying novel drugs and biomarkers for treating endometrial cancer using a high-throughput patient-derived organoid drug discovery and screening platform KU Leuven
How to deal with recurrent ovarian cancer: a new approach. KU Leuven
Ovarian cancer (OC) is the most lethal gynecological cancer. The majority of patients relapse and once recurrence has occurred, treatment options are scarce. Immune checkpoint inhibition has failed. The immune biology of OC is complex and innate immunosuppression is overwhelming. The immune behavior during tumor recurrence is much less elucidated, however, preliminary data from our group also point towards innate immunosuppression. In this ...
JLS / 2008 / DAP3 / OG / 1006 Ghent University
Activities of SGBV Team in ICRH during 2009, fo which financial assistance is required:
1. Harmful traditional practices:
ICRH aims at organising an international course on harmful traditional practices. The focus of this course will be on harmful traditional practices from a human rights and gender perspective, and the consequences on the sexual and reproductive health of women and men.
2. Female genital mutilation ...
Importance of a reliable diagnosis of myometrial lesions using ultrasonography and liquid biopsy biomarkers in clinical gynecological practice. KU Leuven
Malignant myometrial lesions (sarcomas) are highly aggressive and require radical surgery in an oncological centre. Benign myometrial lesions (myomas) may either be managed expectantly, treated medically or by selective uterine artery embolisation or surgically by laparoscopic myomectomy with morcellation. It is of utmost importance to accurately identify sarcomas, not only because any delay in diagnosis is associated with lower survival ...
The continuous search for new approaches improving postoperative outcomes KU Leuven
For further improvements of postoperative outcome, prevention of postoperative nausea and vomiting and adequate pain control are crucial, as these two entities remain the most frequent postoperative complications and hence also most important complaints of patients after surgery. The reduction of PONV and postoperative pain will thus have a large impact on patient well-being and satisfaction.
The overall incidence of PONV after general ...
Epidemiological study of relapse in breast, ovarian and cervical cancers. KU Leuven
Research project in the field of Gyneacology , a non-commercial retrospective clinical study entitled Epidemiological study of relapse in breast, ovarian and cervical cancers and conducted according to the Protocol and the principles of good clinical practices.
The ADNEX risk model for ovarian cancer diagnosis: improving performance across different hospitals and examiners KU Leuven
Ovarian cancer is a common cause of cancer mortality. Detection in
an early stage improves survival, as well as treatment by specialized
gynecological oncologists. Yet many tumors are harmless and are
best managed using a conservative wait-and-see approach. This
implies that good diagnostic and screening approaches are needed.
Research on screening has been unsuccessful, making good
diagnostic strategies even ...