Organisations
Laboratory of Reproductive Genomics KU Leuven
Our group focuses on:
(1) The development of wet-lab and computational methods for single-cell multi-omics analyses –including genome, epigenome and transcriptome analyses of single cells– using microarray and next-generation sequencing technologies. We furthermore automate these methods using customised liquid handling robotics and microfluidics.
(2) The application of these methods to study the nature, rate and mechanisms of ...
Laboratory for Cytogenetics and Genome Research KU Leuven
The Laboratory for Cytogenetics and Genome Research has three focus areas. First, the laboratory is at the forefront of genomic technology development and implementation. During the last five years, the laboratory focused on implementing array CGH in molecular diagnostics and on novel applications of array CGH. A major area of attention is the detection of genome wide CNV and SNP detection in single cells. Currently, the laboratory is ...
Laboratory of Membrane Trafficking (VIB-KUÂ Leuven) KU Leuven
The research in the Laboratory of Membrane Trafficking is focused on the cell biology and trafficking of the g-secretase components. This multiprotein complex has been implicated in a new signal transduction paradigm, called Regulated Intramembrane Proteolysis or RIP and is critical in a wide variety of important cellular activities including embryogenesis, brain development and haematopoiesis. RIP also plays a central role in Alzheimer's ...
Medicinal Chemistry (Rega Institute) KU Leuven
The interests of the Laboratory for Medicinal Chemistry lay in the field of peptide, nucleoside and oligonucleotide chemistry. New substances are synthesized, analyzed and evaluated for activity in vitro. In addition, molecular modeling, NMR and mass spectrometry facilities are available and these units perform supporting research.
- Development of nucleoside derivatives with antiviral (AIDS chemotherapy) and antitumoral ...