Researcher
Wim Annaert
- Disciplines:Intracellular compartments and transport
Affiliations
- Laboratory of Membrane Trafficking (VIB-KU Leuven Center for Brain & Disease Research) (Lab)
Member
From1 Jan 2017 → Today - Laboratory of Membrane Trafficking (VIB-KU Leuven Center for Brain & Disease Research) (Lab)
Responsible
From1 Jan 2006 → Today - Department of Human Genetics (Department)
Member
From1 Oct 1999 → 30 Sep 2002
Projects
1 - 10 of 41 results
- The impact of lysosomal Phospholipase D3 deficiency on activated response microglia regulationFrom1 Oct 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Inter-organelle communication through membrane contact sites in oncology and neurodegenerative diseases (InterAction)From1 Oct 2021 → TodayFunding: BOF - projects, BOF - Concerted Research Project from 1994
- The role of Rer1 in ER-related homeostatic mechanismsFrom1 Jan 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Dynamic super-resolution microscopy: a gateway for cell biologists to understand molecular machines at work in living cells during homeostasis & diseaseFrom1 Jan 2021 → TodayFunding: BOF - scientific equipment program
- The lysosomal exonuclease PLD3 as an endolysosomal flux regulator: impact on neuronal homeostasis and relevance in neurodegeneration.From1 Oct 2020 → TodayFunding: FWO junior postdoctoral fellowship
- Lysosomal Homeostasis in Alzheimer's diseaseFrom25 Sep 2020 → 11 Dec 2020Funding: Own budget, for example: patrimony, inscription fees, gifts
- Targeting dysregulated IP3 receptor-mediated calcium signaling as an early event in Alzheimer’s disease through its Bcl-2-interaction networkFrom21 Sep 2020 → TodayFunding: FWO fellowships
- Unraveling the role of VPS13C in lysosomal homeostasis and interorganellar homeostasis using new cellular and in vivo models.From15 Sep 2020 → TodayFunding: FWO fellowships
- IP3R dysregulation as a proximal event in Alzheimer’s disease: exploring and exploiting Bcl-2 proteinsFrom1 Jan 2020 → TodayFunding: FWO research project
- Unraveling how VPS13C deficiency affects interorganellar lipid transport and lysosomal homeostasis and how this contributes to the neuropathogenesis of Dementia with Lewy BodiesFrom1 Jan 2020 → TodayFunding: FWO research project
Publications
1 - 10 of 77 results
- The microglial lysosomal system in Alzheimer's disease: Guardian against proteinopathy(2021)
Authors: Zoë Van Acker, Anna Perdok, Marine Bretou, Willem Annaert
Number of pages: 18 - Assembly of gamma-secretase occurs through stable dimers after exit from the endoplasmic reticulum(2021)
Authors: Rosanne Wouters, Christine Michiels, Ragna Sannerud, Bertrand Kleizen, Katleen Dillen, Wendy Vermeire, Abril Escamilla Ayala, David Demedts, Randy Schekman, Willem Annaert
Number of pages: 26 - The role of Bcl-2 proteins in modulating neuronal Ca2+ signaling in health and in Alzheimer's disease(2021)
Authors: Manon Callens, Nina Kraskovskaya, Kristina Derevtsova, Willem Annaert, Geert Bultynck, Ilya Bezprozvanny, Tim Vervliet
Number of pages: 13 - BNIP3 promotes HIF-1 alpha-driven melanoma growth by curbing intracellular iron homeostasis(2021)
Authors: Mónica Vara Pérez, Matteo Rossi, Chris Van den Haute, Hannelore Maes, Maria Livia Sassano, Vivek Venkataramani, Bernhard Michalke, Erminia Romano, Kristine Rillaerts, Abhishek Garg, et al.
Number of pages: 22 - The Nanoscopic Organization of Synapse Structures: A Common Basis for Cell Communication(2021)
Authors: Xiaojuan YANG, Willem Annaert
Number of pages: 15 - BNIP3 IN MELANOMA: SITTING ON THE IRON THRONE Unraveling the role of BNIP3 in mitochondrial homeostasis, metabolism and melanoma growth(2021)
Authors: Mónica Vara Pérez, Patrizia Agostinis, Willem Annaert
- Contribution of rare homozygous and compound heterozygous VPS13C missense mutations to dementia with Lewy bodies and Parkinson's disease(2021)
Authors: Stefanie Smolders, Stephanie Philtjens, David Crosiers, Anne Sieben, Elisabeth Hens, Bavo Heeman, Sara Van Mossevelde, Philippe Pals, Bob Asselbergh, Roberto Dos Santos Dias, et al.
Number of pages: 15 - ATP13A3 is a major component of the enigmatic mammalian polyamine transport system(2021)
Authors: Norin Hamouda, Chris Van den Haute, Roeland Vanhoutte, Ragna Sannerud, Mujahid Azfar, Rupert Mayer, Alvaro Cortes Calabuig, Johannes Swinnen, Patrizia Agostinis, Veerle Baekelandt, et al.
Number of pages: 17 - PIKfyve activity is required for lysosomal trafficking of tau aggregates and tau seeding(2021)
Authors: Alberto Carpinteiro Soares, Andreia Ferreira, Jonas Marieen, Charlotte Delay, Edward Lee, John Q Trojanowski, Dieder Moechars, Willem Annaert, Louis De Muynck
Number of pages: 15 - Superparamagnetic Nanoparticles for Lysosome Isolation to Identify Spatial Alterations in Lysosomal Protein and Lipid Composition.(2020)
Authors: Arun Kumar Tharkeshwar, David Demedts, Willem Annaert
Pages: 100122