< Back to previous page
Laboratory of Membrane Trafficking (VIB-KU Leuven)
Main organisation:Research Group Molecular Neurobiology (VIB-KU Leuven)
Lifecycle:1 Jan 2006 → Today
The research in the Laboratory of Membrane Trafficking is focused on the cell biology and trafficking of the g-secretase components. This multiprotein complex has been implicated in a new signal transduction paradigm, called Regulated Intramembrane Proteolysis or RIP and is critical in a wide variety of important cellular activities including embryogenesis, brain development and haematopoiesis. RIP also plays a central role in Alzheimer's disease as it mediates the final step in the release of amyloid b from the amyloid precursor protein (APP).
Disciplines:Laboratory medicine, Palliative care and end-of-life care, Regenerative medicine, Other basic sciences, Other health sciences, Nursing, Other paramedical sciences, Other translational sciences, Other medical and health sciences