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Researcher
Eveline Lescrinier
- Disciplines:Biomarker discovery and evaluation, Drug discovery and development, Medicinal products, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences, Bioinformatics and computational biology
Affiliations
- Medicinal Chemistry (Rega Institute) (Division)
Responsible
From1 Aug 2016 → Today - Medicinal Chemistry (Rega Institute) (Division)
Member
From1 Oct 1999 → Today
Projects
1 - 10 of 21
- From experimental NMR data towards a software tool to predict optimal sequences for therapeutic morpholino oligonucleotidesFrom15 Jul 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Stereo-controlled synthesis of artificial genetic systems with modified sugar phosphate backboneFrom10 Nov 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Artificial genetic systems with stereocontrolled sugar-phosphate backbone: towards advanced therapy and synthetic biology.From1 Jan 2021 → TodayFunding: FWO research project
- Molecular modelling tools to design artificial enzymesFrom18 Nov 2020 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- An NMR facility tailored for biomedical researchFrom1 May 2020 → TodayFunding: FWO Medium Size Research Infrastructure
- Synthesis of nucleoside analogues as antiviral and antibacterial agentsFrom10 Feb 2020 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Selection of nucleic acids aptamers with four non-canonical bases for biomedical applicationsFrom1 Jan 2020 → 31 Dec 2020Funding: FWO research grant KAN
- Streamlining the route of phosphonate XNA from chemistry to applicationFrom1 Oct 2019 → 30 Sep 2023Funding: IOF - technology concept exploration, BOF - projects
- New genetic systems with four synthetic nucleobases: towards advance therapy and synthetic biologyFrom1 Oct 2018 → 15 Dec 2021Funding: FWO fellowships
- Synthesis and structure determination of phosphonate oligonucleotidesFrom17 Sep 2018 → 17 Sep 2022Funding: Own budget, for example: patrimony, inscription fees, gifts
Publications
1 - 10 of 90
- Characterization of an HNA aptamer suggests a non-canonical G-quadruplex motif(2023)
Authors: Jérôme Rihon, Eveline Lescrinier
Pages: 7736 - 7748 - Synthesis, antiviral activity, and computational study of beta-D-xylofuranosyl nucleoside phosphonates(2023)
Authors: Yuqing Xu, Elisabetta Groaz, Jérôme Rihon, Eveline Lescrinier
- Synthesis, Structure-Activity Relationships, and Antiviral Profiling of 1-Heteroaryl-2-Alkoxyphenyl Analogs as Inhibitors of SARS-CoV-2 Replication(2022)
Authors: Laura Vangeel, Erion Lyoo, Eveline Lescrinier, Pieter Leyssen, Dirk Jochmans, Johan Neyts, Steven De Jonghe
- Curing Cats with Feline Infectious Peritonitis with an Oral Multi-Component Drug Containing GS-441524(2021)
Authors: Eveline Lescrinier
- Structure and folding of XNA aptamers studied by computational and experimental methods(2021)
Authors: Charles-Alexandre Mattelaer, Eveline Lescrinier, Mathy Froeyen
- Cyclic Peptides as T-Type Calcium Channel Blockers: Characterization and Molecular Mapping of the Binding Site(2021)
Authors: Anne-Sophie Depuydt, Jérôme Rihon, Eveline Lescrinier, Steve Peigneur, Jan Tytgat
Pages: 1 - 11 - Determination of tacrolimus, three mono-demethylated metabolites and a M1 tautomer in human whole blood by liquid chromatography - tandem mass spectrometry(2021)
Authors: Pieter Annaert, Eveline Lescrinier, Dirk Kuypers
- Functional and Molecular Characterization of the Halomicrobium sp. IBSBa Inulosucrase(2021)
Authors: Eveline Lescrinier, Wim Van den Ende
- Stable Hairpin Structures Formed by Xylose-Based Nucleic Acids(2021)
Authors: Charles-Alexandre Mattelaer, Eveline Lescrinier
Pages: 1638 - 1645 - Molecular Dynamics Simulations in Drug Discovery and Pharmaceutical Development(2021)
Authors: Eveline Lescrinier