Levaraging transcriptomic and metabolic analysis towards future therapeutics in HTLV-1 triggered Adult T-cell Lymphoma/Leukemia KU Leuven
HTLV-1 induced Adult T-cell Lymphoma/Leukemia (ATL) is a complex opportunistic malignancy with two components that must be addressed during treatment: a delicate balance between cell death and cell survival/proliferation of the tumoral CD4+ clone vs. cell activation, cell death and proliferation of anti-leukemic CD8+ cells. This project will combine unbiased transcriptomic and metabolomic analysis of ATL cohorts. Transcriptomic and ...