Laboratory of Clinical and Epidemiological Virology (Rega Institute)
The research team of Prof. Vandamme is investigating factors influencing antiviral treatment response in HIV infected patients with a special focus on the impact of virus drug resistance. The team is responsible for drug resistance testing in clinical practice at the local AIDS Reference Laboratory. Another research topic involves the evolution and molecular epidemiology of human viruses, seeking to understand in particular the origin and evolution of HIV and HTLV, the only two pathogenic human retroviruses known so far. Prof. Vandamme organizes the yearly International Bioinformatics Workshop on Virus Evolution and Molecular Epidemiology, in 2006 it will be 12 years (http://www.kuleuven.ac.be/aidslab/veme.htm). The research team of Professor Van Ranst works on the molecular epidemiology of rotaviruses, papillomaviruses, RSV, and enteroviruses. The team is also developing and testing a vaccine against hantaviruses. Other reserch projects investigate the host genetic susceptibility for viral infections.