Projects
The crucial importance of timing of brain stimulation: Towards brain-oscillation-synchronized transcranial magnetic stimulation for the treatment of epilepsy. Ghent University
Transcranial magnetic stimulation (TMS) is a non-invasive brain stimulation technique. It is a promising treatment method for patients with refractory epilepsy. However, the overall response rates remain modest and there is high inter-individual variability. Recent findings, mostly derived after motor cortex stimulation, suggest that the exact timing of the delivery of TMS pulses has crucial effects on the individual brain response. This ...
Priming stimulation: a multimodal approach to evaluate the effects of theta-burst transcranial magnetic stimulation priming on prefrontal cortex functioning in healthy and depressed individuals Ghent University
Intermittent theta-burst stimulation (iTBS) has been increasingly used to target prefrontal brain regions, such as the dorsolateral prefrontal cortex (DLPFC), to optimize therapeutic outcomes in patients suffering from major depressive disorder. However, despite the promising outcomes, clinical efficacy remains rather modest. Interestingly, fundamental research targeting the motor cortex has suggested the use of priming techniques to enhance ...
Role of afferent activation after esophageal stimulation by distention and perfusion of different solutions simulating conditions of gastro-oesophageal reflux disease. KU Leuven
Systematic study of extinction and re-ignition modelling through finite rate chemistry in LES simulations of buoyant flames Ghent University
LES (Large Eddy Simulations) for turbulence is well established. In turbulent reacting flows, there is a range of options for the modelling of combustion and turbulence - chemistry interaction (TCI). A popular approach in fire simulations is EDC (Eddy Dissipation Concept). It is common practice to assume infinitely fast chemistry to date. However, a model for extinction is required then, which is typically based on temperature or enthalpy. In ...
Power to olefins: Computation fluid dynamics simulations of electrified rotor stator steam cracking reactor. Ghent University
Steam cracking is and will remain the most commonly applied technology for the production of lower olefins in the common decades. However, it faces some major environmental issues as the furnaces of the steam crackers in Flanders are responsible for 50% of the total CO2 emission of the chemical industry. A radically new reactor concept for drastic heat transfer intensification, that will be investigated in this project, is that of an ...
Integrating Process Simulations into Virtual Environments for Training KU Leuven
This work researches the use of already available process simulations to develop virtual environment for training, with a focus on games. The work is divided into a first half focusing on the technical challenges: first when attempting to establish a direct connection (the focus is on the study of ActiveX for Aspen Hysys), and also when attempting the development of a surrogate model to integrate in the environment (the focus is on the ...
Combining p-values and effect sizes in the meta-analysis of single-case experiments: Monte Carlo simulations, R package, and applications on treating challenging behaviour among persons with intellectual disabilities. KU Leuven
Development of models for numerical simulations of turbulent spray combustion Ghent University
The proposal concerns accurate numerical CFD (Computational Fluid Dynamics) simulations of turbulent flames, coming from fuel droplet sprays, within acceptable computing times. Two techniques are used: transported PDF (Probability density function) and LES (Large-eddy simulations). Attention will ne focused onto modelling of the conditional scalar dissipation rate and onto two-way coupling.
First-principles 3D reactor design: Large Eddy Simulation and Direct Numerical Simulation with detailed chemistry Ghent University
The rising computational power makes that new innovations are possible of which 5
years ago one could not even dream. This is in particular important for chemical
reactor and reaction engineering where Process Intensification drives researchers to
think outside the box. In the academic as well as the industrial world, innovations are
more and more based on 3D reactor simulations incorporating chemical reactions. ...