Projects
In vitro system for exploring cellular force transmission during angiogenesis. KU Leuven
Organ function is dependent on the formation of a functional blood circulatory network. Angiogenesis is the process of forming new blood capillaries from pre-existing ones, where endothelial cells (ECs) residing on capillary walls invade the surrounding extracellular matrix (ECM) and form angiogenic sprouts. Cell invasion is strongly dependent on the ability of cells to generate traction forces, rendering traction generation fundamental to ...
Data driven modeling of cell shapes and movements in multicellular systems. KU Leuven
Unraveling how cells move and self organize in a multicellular setting
is crucial for understanding a variety of biological processes like
embryogenesis, tissue formation and many diseases. This is a highly
dynamic process, where cells move and change shape guided by
biochemical as well as physical cues. A precise reconstruction of cell
shape over time provides detailed information on force generation ...
Enhanced silicate weathering as CO2 removal strategy in coastal environments. University of Antwerp
Global circulation and mesoscale modeling of the Martian atmosphere: Applied to the detection of subsurface liquid water KU Leuven
The search for life in our solar system has been one of the most interesting topics in natural sciences. Based on the observations for Earth, the keystone of life is liquid water. On Mars, water ice exists under the surface. Moreover, a recent discovery has proven the existence of a liquid water lake beneath the south polar cap. Considering the possibility that Early Mars was covered with an ocean, if Mars had harboured life, the life on ...
Immune effector cell therapy for hematological malignancies with a focus on acute myeloid leukemia and multiple myeloma. University of Antwerp
Neurophysiology of cognition in multiple sclerosis. Vrije Universiteit Brussel
Finding a highly accurate biomarker for CDiMS would be game changing for patients adjusting their life-plans, neurologists advising their patients on optimal treatment strategies, and researchers developing new ...
Machine learning platform for better cardiovascular health assessment and risk stratification KU Leuven
Precise description of cardiovascular health and risk assessment are essential for optimal prevention and treatment strategies, but require a complex integration of many factors. The specific objectives of this project are: (1) Applying machine-learning (ML) algorithms to the available longitudinal, highly standardized, general population data to assess the complexity of clinical and behavioral variables, cardiac imaging sequences and ...
Simulation of gas transport during controlled atmosphere storage of pome fruit using computational fluid dynamics and discrete element modelling KU Leuven
Pear fruit is a major export product of Flanders. To preserve quality after harvest, pears are commonly stored in a controlled atmosphere (CA), in which the oxygen concentration is reduced and carbon dioxide concentration is elevated to minimize respiration. Too low oxygen concentrations, however, lead to fermentative decay. A recent innovation uses dynamic controlled atmosphere (DCA). In DCA the oxygen concentration is dynamically adapted to ...
DNA-only nanosensor technology empowers ultrasensitive multiplexing at the point of care KU Leuven
Recent trends in (early-stage) disease diagnosis have been driven by an increasing interest in detecting very low disease biomarker concentrations within small sample volumes. The related technological challenge is to design and develop very sensitive and accurate diagnostic tools that can attain this goal. In this context, DNA has been studied extensively over the years as an alternative building block for traditionally used proteins with ...