Projects
Unravelling structural motives of intrinsically unstructured proteins employing Raman optical activity: Understanding the basis of neurodegenerative diseases University of Antwerp
Response Modulation in psychopathy: AttentionalModulation of Emotional Processing. Vrije Universiteit Brussel
Acquisition, generalisation and extinction of pain-related fear: An observational learning account. KU Leuven
Higher Order Modelling for First Order Solvers KU Leuven
Many common computational problems can be posed as model expansion problems, where the task is to find a solution satisfying a set of constraints. Many different paradigms and approaches exist to solve these problems. Likewise, there are many languages to express these problems in. Some of these are standardized, such as Answer Set Programming (ASP) or Minizinc. For some languages there is only one system, like the FO(.) language. The ...
Large-eddy Simulation and Optimal Coordinated Control of Wind-farm Boundary Layers KU Leuven
In wind farms, velocity deficits in the wakes originating from upstream turbines result in a significant decrease in power extraction in downstream turbine rows. The current control paradigm in industry optimizes power extraction at the turbine level, and does not account for these interactions, leading to sub-optimal wind-farm efficiencies. The current dissertation investigates the use of a coordinated control approach that maximizes power ...
Aging and neuroplasticity: changes in brain structure, function, and connectivity in relation to motor coordination. KU Leuven
Cross-Layer Self-Adaptivity for Ultra-Low Power Responsive IoT Devices: Analysing Task Hierarchy and Task Adaptivity at Different Optimisation Levels KU Leuven
In the past 50 years, the world has seen a steady rise in devices which are connected to the internet.
This rise in connected devices has led to a vision where every physical device is connected to the world, called the Internet-of-Things.
The vision enables many opportunities across different application domains: smart healthcare, smart agriculture, smart homes,...
However, to bring this vision to fruition, those devices need ...
Optogenetics and genetic brain transduction in non-human primates. KU Leuven
Although the role of the ventral tegmental area (VTA) in reward-driven behaviors is supported by electrophysiology (Schultz et al., 1997) and electrical microstimulation (Arsenault et al., 2014), the specific role of the VTA-Nucleus accumbens (NAcc) pathway in such behaviors remains untested in primates. We will examine the neural and behavioral role of this specific circuit in macaques using a pathway-selective double-infection technique ...
Local and systemic immune interactions in malignant gliomas KU Leuven
Glioblastoma (GBM), the most frequent primary intrinsic brain tumor, is without any doubt one of the most devastating diseases known to mankind. GBM are currently being treated with neurosurgical resection followed by radio- and chemotherapy. However, despite this treatment, prognosis for these patients is grim with a median survival of only 15 months and less than 20% 3-year survival rates. Already at diagnosis, GBM cells are infiltrating ...