Organisations
Centre for Molecular and Vascular Biology KU Leuven
The Center for Molecular and Vascular Biology performs research related to the following topics:- Pathogenesis of thrombosis and bleeding. - Development of assays for the diagnosis of thrombosis and bleeding. – Signalling and transcription factor regulation in megakaryocytes and platelets. - Genetics for bleeding and thrombotic disorders. –(patho)physiology of megakaryopoiesis. – Role of transcription factors in endothelial heterogeneity. – ...
Department of Biotechnology Ghent University
Department of Materials, Textiles and Chemical Engineering Ghent University
Department of Medical and Forensic Pathology Ghent University
Faculty of Pharmaceutical Sciences KU Leuven
The Faculty of Pharmaceutical Sciences consists of one department, the Department of Pharmaceutical and Pharmacological Sciences. For more information on research topics see the department.
Laboratory of Glia Biology (VIB-KU Leuven) KU Leuven
The long-term goal of Laboratory of Glia Biologyis to understand the molecular mechanisms that control development and function of astrocytes in vivo, and how they interact with neurons.
Our strategy is to use astrocytes isolated from mouse brain as a starting point. This allows us to effectively take a “bottom up” approach to astrocyte function. In a first step, we are combining state-of-the-art biochemical and physiological techniques ...
Laboratory of Molecular and Cellular Signaling KU Leuven
The main focus of the research of the Laboratory of Molecular and Cellular Signaling is Ca2+ signalling in health and disease. We have a longstanding tradition in the investigation of cellular Ca2+ signalling both in single cells and in cell populations. We have developed a number of state-of-the-art techniques including fluorescence and confocal microscopy, luminescence and fluorescence multiplate reader, flux experiments with 45Ca2+ and a ...
Laboratory of Protein Phosphorylation and Proteomics KU Leuven
- We investigate the regulation of (patho)physiological processes via reversible protein phosphorylation, and explore the therapeutic potential of the kinases and phosphatases involved. Focus is on Protein Kinase D (PKD) and Protein Phosphatase 2A (PP2A), but increasingly also on broader (kinome and phosphatome wide) approaches to systematically identify kinases/phosphatases that are implicated in (patho)physiological ...
Laboratory of Structural Neurobiology KU Leuven
The Laboratory of Structural Neurobiology is interested in understanding the structural basis of ion channel function. Ion channels are integral membrane proteins that act as molecular switches of electrochemical signaling in the central nervous system. Our specific goal is to understand the structural determinants of ligand recognition, the mechanism of channel gating and ion selection and permeation. Our methodological approach is based on ...