The study of classical and alternative activation in human induced pluripotent stem cell-derived microglia and macrophages. University of Antwerp
Laboratory for Experimental Hematology (LEH), Vaccine & Infectious Disease Institute (VAXINFECTIO)
Neuroinflammation occurs in all central nervous system (CNS) pathologies and can be defined as the activation of local and peripheral infiltrating immune cells, with the key players being brain-resident microglia and blood-borne infiltrating macrophages. While growing evidence ascribes different roles to microglia and macrophages in neuro-inflammation, the main interest in both phagocytes, with regard to therapeutic strategies, is their ability ...