Molecular insights in SARS-CoV-2 pathogenesis and epidemiology. University of Antwerp
Medical Genetics (MEDGEN), Laboratory of Medical Microbiology (LMM), Laboratory of cell biology and histology, Translational Neurosciences (TNW), Laboratory Experimental Medicine and Pediatrics (LEMP)
Infection with SARS-CoV-2 mostly leads to a mild self-limiting respiratory tract illness, however, some patients progress to develop severe progressive pneumonia, multiorgan failure, and death. The project aims to determine factors that dictate the severity of COVID-19. Firstly, guided by our prior data of interaction of certain mucins with the ACE2 receptor and the clinical evidence of excessive mucin production in severe COVID-19 illness, we ...