Publications
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A Kv channel with an altered activation gate sequence displays both 'fast' and 'slow' activation kinetics Ghent University University of Antwerp
Plasma activation of electrospun scaffolds for neural tissue engineering Ghent University
An alerting high incidence of peripheral nerve injuries (PNI) reaching over one million cases worldwide is still lingering over the centuries. This is due to the fact that peripheral nerves are not protected like the brain and the spinal cord by a bone tissue and a nerve-blood barrier, making them susceptible to physical, chemical, thermal and/or ischemic damages at any anatomic site. Luckily, unlike the central nervous system having a very ...
Assisted oocyte activation: role of calcium and PLCzeta Ghent University
Tijdens de bevruchting van een eicel, zal de zaadcel niet alleen zijn genetisch materiaal binnenbrengen, maar de eicel ook activeren. De eicel is namelijk in rust, geblokkeerd in de metafase van de tweede meïotische deling. Eicelactivatie is een complex proces en omvat naast de afwerking van de meïotische deling (gekenmerkt door de uitstoting van het tweede poollichaampje), de verharding van de zona pellucida, de vorming van de pronucleus en de ...
Effect of heat treatment intensity on the survival, activation and subsequent outgrowth of Byssochlamys nivea ascospores Ghent University
Recent Insights in Pyrin inflammasome activation : identifying potential novel therapeutic approaches in Pyrin-associated autoinflammatory syndromes Ghent University Hasselt University Flanders Institute for Biotechnology University of Antwerp
Pyrin is a cytosolic protein encoded by the MEFV gene, predominantly expressed in innate immune cells. Upon activation, it forms an inflammasome, a multimolecular complex that enables the activation and secretion of IL-1 beta and IL-18. In addition, the Pyrin inflammasome activates Gasdermin D leading to pyroptosis, a highly pro-inflammatory cell death. Four autoinflammatory syndromes are associated with Pyrin inflammasome dysregulation: ...
Activation of catalysts in commercial scale fixed-bed reactors : dynamic modelling and guidelines for avoiding undesired temperature excursions Ghent University
During the exothermic gas phase activation (e.g. reduction) or passivation (oxidation) of a catalyst in a commercial scale fixed bed, the interaction of the heat wave propagation phenomenon and the (desired) exothermic gas-solid reaction(s) may give rise to local temperature excursions way beyond the adiabatic temperature rise of the reactions. Inspired by a decoking study by Westerterp et al. (1988), a full dynamic model for generic gas-phase ...