The role of BMP signaling in early arterial differentiation. KU Leuven
During embryonic development, the cardiovascular system, comprising the heart and vessels, develops as first organ system, providing the embryo with necessary oxygen and nutrients. Already early on in cardiovascular development, vessels are characterised either by arterial or venous markers. The correct differentiation of arteries and veins, called arteriovenous differentiation, is a crucial step in cardiovascular development, as impaired ...