Organic synthesis is a powerful method to interrogate biological processes, complementing genetics studies. In this project, innovative synthetic strategies will be developed that can find utility in biology research. As a primary focus, applications in plant biology research will be targeted, as several U+2018small moleculesU+2019 have recently emerged as potent tools to study and control cell biological processes.
Light-Stabilised Dynamic Materials. Ghent University
We very recently discovered a new conceptual approach to design polymer materials that can be reversibly crosslinked upon visible light irradiation, yet importantly be kept stable by light. Here, we are devoted to develop and exploit the potential of this new class of U+2018light-stabilised dynamic materialsU+2019,
which we believe constitutes a key step in the development of next generation light-responsive materials.
Metabolic fingerprinting towards diagnosis and prognosis of cow's milk allergy in children. Ghent University
Given the emerging evidence for the involvement of the gut microbiome in the onset of food allergy
and its resolution, this project will rely on our metabolomics platform and microbial analysis of CMA patients' biofluids, for identifying prognostic biomarkers. Specific bacterial groups involved in the biomarker formation, will be manipulated or administered to mice to aid in biomarker qualification.
Dietary exposure to multi-mycotoxins as a predisposing factor for oesophageal squamous cell carcinoma in Malawi Ghent University
Malawi has the highest age-standardized rate of oesophageal carcinoma (ESCC), and relies on maize as staple food. Common mycotoxins in maize - fumonisins and aflatoxins- have been linked with an increased risk of ESCC in areas of intensive maize farming. This study aims at measuring the extent of mycotoxins in maize, and establishing associations between exposure and risk of ESCC-development.
Development of multiplexed plasma reactor for wastewater treatment Ghent University
The project is based on improving the energy efficiency of wastewater treatment process by developing a non-thermal plasma reactor, capable of producing and dosing reactive species in situ in wastewater for the removal of pollutants. Utilization of non-thermal plasma reactors require significantly less energy as compared to conventional one for wastewater treatment.
Spectator Ligand Effects in Palladium Catalysis (SPEPCAT). Ghent University
The design and understanding of well-defined organometallic architectures are key to modern catalysis. The focus of this project is the need for ever active and longer living complexes leading to the formation of C-C and C-N bonds. We address these challenges by developing a novel paradigm
in well-defined palladium catalysis and investigating the stabilizing/reactivity role of supporting U+201CspectatorU+201D ligands.
Catalytic Conversion of CO2 to Chemicals Ghent University
The discovery of efficient technologies enabling the use of CO2 as a starting material for chemical synthesis is one of the most significant challenges of our time. They could serve the dual purpose of reducing CO2 emissions and producing value-added chem
Data Driven Molecular Modelling for Reactor Design Ghent University
Chemical reactor design and optimization based on insights and data on a molecular level can become reality in the coming decade. Multiscale simulations including all elementary reaction steps in a full microkinetic model, with information on catalyst str
An in situ investigation of the surface chemistry during the nucleation and growth of cobalt and nickel using atomic layer deposition Ghent University
This proposal aims to provide a thorough understanding of the surface chemistry and physics during atomic layer deposition (ALD) of cobalt and nickel for applications in microelectronics and catalysis. In microelectronics, ALD of high quality, continuous