Researcher
Tom Taghon
- Disciplines:Developmental biology, Hematology not elsewhere classified, Immunology not elsewhere classified
Affiliations
- Department of Diagnostic Sciences (Department)
Member
From1 Oct 2018 → Today - Dean's Office of the Faculty of Medicine and Health Sciences (Administrative office)
Member
From1 Jul 2002 → 31 Oct 2002 - Department of Clinical chemistry, microbiology and immunology (Department)
Member
From1 Jan 1998 → 30 Sep 2018
Projects
11 - 20 of 48
- Identification of the molecular drivers of ab vs. gd T cell development at single cell resolution in humanFrom1 Oct 2022 → TodayFunding: FWO junior postdoctoral fellowship
- SpatialConnect: linking tissue biology to the new era of single-cell spatial transcriptomicsFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- The generation of bona fide T cell precursors for cell therapyFrom15 Apr 2022 → TodayFunding: IOF - technology validation in lab
- Functional analysis of the RNA helicase DHX15 in T-cell acutelymphoblastic leukemiaFrom1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- Origin and molecular drivers of T cell and dendritic cell development in the human thymus.From1 Oct 2021 → TodayFunding: BOF - projects
- Deciphering the functional phenotype of γδ T cells in spondyloarthritis.From1 Oct 2021 → 31 Oct 2021Funding: BOF - doctoral mandates
- Rapid ex-vivo detection, quantification and characterisation of cell-mediated immune responses induced by natural infection or vaccination with SARS-CoV-2 orr other pathogens.From1 Apr 2021 → 31 Mar 2023Funding: IOF - technology validation in lab
- Unraveling the role of GATA3 in BCP-ALLFrom1 Mar 2021 → TodayFunding: Foundations, funds and other with scientific goal
- Functional characterization and expansion of thymus seeding precursors in humanFrom1 Mar 2021 → TodayFunding: Foundations, funds and other with scientific goal
- Epigenetic drivers of human αβ and γδ T cell differentiation at the single cell level.From1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
Publications
1 - 10 of 137
- Type 1 immunity enables neonatal thymic ILC1 production(2024)
Authors: Peter Tougaard, Mario Ruiz Pérez, Wolf Steels, Jelle Huysentruyt, Bruno Verstraeten, Jessica Vetters, Tatyana Divert, Amanda Gonçalves, Ria Roelandt, Nozomi Takahashi, et al.
- Dendritic cell-biased precursors support early human thymopoiesis(2023)
Authors: Tom Taghon, Kai Ling Liang
Pages: 389 - 390 - Single-cell profiling identifies a novel human polyclonal unconventional T cell lineage(2023)
Authors: Lore Billiet, Laurenz De Cock, Guillem Sanchez Sanchez, Rupert Mayer, Glenn Goetgeluk, Stijn De Munter, Melissa Pille, Joline Ingels, Hanne Jansen, Karin Weening, et al.
- RNA helicase DHX15 exemplifies a unique dependency in acute leukemia(2023)
Authors: Hao Guo, Jin Xu, Peiqi Xing, Qilong Li, Donghai Wang, Chao Tang, Bruno Palhais, Juliette Roels, Jiaxu Liu, Sa Pan, et al.
Pages: 2029 - 2043 - The Wiskott–Aldrich syndrome protein is required for positive selection during T-cell lineage differentiation(2023)
Authors: John Avila, Guillem Sanchez Sanchez, Glenn Goetgeluk, Stijn De Munter, Hanne Jansen, Lore Billiet, Karin Weening, Haipeng Xue, Eva Pascal, Lucas Deseins, et al.
- Intrathymic dendritic cell-biased precursors promote human T cell lineage specification through IRF8-driven transmembrane TNF(2023)
Authors: Kai Ling Liang, Juliette Roels, Marieke Lavaert, Tom Putteman, Lena Böhme, Laurentijn Tilleman, Imke Velghe, Valentina Pegoretti, Inge Van de Walle, Stephanie Sontag, et al.
Pages: 474 - 486 - Pre-clinical evaluation of the hypomethylating agent decitabine for the treatment of T-cell lymphoblastic lymphoma(2023)
Authors: Tom Putteman, Mattias Landfors, Lindy Reunes, Wouter Van Loocke, Morgan Thenoz, Natalia Mackowska-Maslak, Tom Taghon, Marc R. Mansour, Nadine Farah, Koen Norga, et al.
- Transcriptional dynamics and epigenetic regulation of E and ID protein encoding genes during human T cell development(2022)
Authors: Juliette Roels, Jolien Van Hulle, Marieke Lavaert, Anna Kuchmiy, Steven Strubbe, Tom Putteman, Bart Vandekerckhove, Georges Leclercq, Filip Van Nieuwerburgh, Lena Böhme, et al.
- Identification and purification of human T cell precursors(2022)Edition: 2Series: Methods in Molecular Biology (MIMB)
Authors: Inge Van de Walle, Nina Lambrechts, Anaïs Derveeuw, Marieke Lavaert, Juliette Roels, Tom Taghon
Pages: 315 - 333 - TXNIP promotes human NK cell development but is dispensable for NK cell functionality(2022)
Authors: Sigrid Wahlen, Sylvie Taveirne, Wouter Van Loocke, Els Van Ammel, Filip Van Nieuwerburgh, Tom Taghon, Pieter Van Vlierberghe, Georges Leclercq