Deciphering the functional phenotype of γδ T cells in spondyloarthritis.

Accumulating evidence points towards the crucial role of γδ T lymphocytes in the pathogenesis of spondyloarthritis (SpA). The project aims to elucidate their exact influence in disease development and different organ involvement. This truly translational project combines cutting-edge analysis of the multilevel regulation of immune cell function in unique patient samples with innovative research on mouse model of SpA.