Researcher
Sophie Janssens
- Keywords (Ghent University):IRE1, dendritic cell biology, unfolded protein response
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Adaptive immunology, Bacteriology
- Disciplines (Ghent University):Cell signalling, Inflammation, Innate immunity, Intracellular compartments and transport
- See also: Sophie Janssens (Flanders Institute for Biotechnology)
Affiliations
- Department of Internal Medicine and Pediatrics (Department)
Member
From1 Oct 2018 → Today - Janssens Lab (Research group)
Responsible
From1 Mar 2018 → Today - Lambrecht and Hammad Lab (Research group)
Member
From1 Jan 2017 → 28 Feb 2018 - Department of Internal medicine (Department)
Member
From1 Mar 2011 → 30 Sep 2018 - Department of Biomedical molecular biology (Department)
Member
From1 Apr 1998 → 30 Sep 2007
Projects
1 - 10 of 13
- LNP-DECODE: Deciphering the adjuvants activity of lipid nanoparticle-based mRNA vaccines in primary dendritic cellsFrom1 Jan 2024 → TodayFunding: BOF - projects
- Decoding tumor antigens: dendritic cell maturation within the tumor environmentFrom1 Oct 2023 → TodayFunding: BOF - projects
- Molecular mechanism and functional implications of the AGR2-IRE1ß axis in goblet cell homeostasisFrom1 Oct 2022 → TodayFunding: FWO junior postdoctoral fellowship
- SpatialConnect: linking tissue biology to the new era of single-cell spatial transcriptomicsFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Dissecting the molecular signals that drive immunogenic versus homeostatic maturation in dendritic cells. An old question revisited.From1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- Understanding the role of Notch in Dendritic Cell biologyFrom1 Nov 2021 → TodayFunding: FWO fellowships
- Replacement and extension of basic infrastructure in the histology core facility.From1 Dec 2020 → 30 Nov 2022Funding: BOF - scientific equipment program
- IRE1 as a regulator of apoptotic cell engulfment in macrophages.From1 Nov 2020 → TodayFunding: FWO fellowships
- The IRE1/XBP1 signaling axis in dendritic cell-mediated anti-tumor immune responsesFrom15 Nov 2019 → 31 Aug 2023Funding: BOF - doctoral mandates
- A novel role for the IRE1/XBP1 branch in dendritic cells: a signaling cascade matures.From1 Oct 2018 → 30 Sep 2022Funding: FWO fellowships
Publications
11 - 19 of 19
- Type III collagen is important for collagen fibrillogenesis and for dermal and cardiovascular development(2015)Volume: 23
Authors: Sanne D'hondt, Brecht Guillemyn, Sofie Symoens, Wendy Toussaint, Leen Vanhoutte, Riet De Rycke, Paul Coucke, Bart Lambrecht, Patrick Segers, Anne De Paepe, et al.
Pages: 110 - 110 - Emerging functions of the unfolded protein response in immunity(2014)
Authors: Sophie Janssens, Bali Pulendran, Bart Lambrecht
Pages: 910 - 919 - HSPB1 facilitates the formation of non-centrosomal microtubules(2013)
Authors: Leonardo Almeida-Souza, Bob Asselbergh, Vicky De Winter, Sofie Goethals, Vincent Timmerman, Sophie Janssens
- Acute injury in the peripheral nervous system triggers an alternative macrophage response(2012)
Authors: Elke Ydens, Anje Cauwels, Bob Asselbergh, Sofie Goethals, Lieve Peeraer, Guillaume Lornet, Leonardo Almeida-Souza, Jo A Van Ginderachter, Vincent Timmerman, Sophie Janssens
- The PIDDosome, DNA-damage-induced apoptosis and beyond(2012)
Authors: Sophie Janssens, A Tinel
Pages: 13 - 20 - Microtubule dynamics in the peripheral nervous system: a matter of balance(2011)
Authors: Leonardo Almeida-Souza, Vincent Timmerman, Sophie Janssens
Pages: 267 - 270 - Increased monomerization of mutant HSPB1 leads to protein hyperactivity in Charcot-Marie-tooth neuropathy(2010)
Authors: Leonardo Almeida-Souza, Sofie Goethals, Vicky de Winter, Ines Dierick, Rodrigo Gallardo, Joost Van Durme, Joy Irobi, Jan Gettemans, Frederic Rousseau, Joost Schymkowitz, et al.
Pages: 12778 - 12786 - Toll-like receptor expression in the peripheral nerve(2010)
Authors: Sofie Goethals, Elke Ydens, Vincent Timmerman, Sophie Janssens
Pages: 1701 - 1709 - p53-induced protein with a death domain (PIDD) isoforms differentially activate nuclear factor-kappaB and caspase-2 in response to genotoxic stress(2008)
Authors: S Cuenin, A Tinel, Sophie Janssens, J Tschopp
Pages: 387 - 396