Researcher
Simon Van Herck
- Keywords:STING, Nanomedicine, cancer immunotherapy, Checkpoint inhibition
- Disciplines:Applied immunology, Particle design and technology, Cancer therapy, Biopharmaceuticals, Nanochemistry
Affiliations
- Department of Pharmaceutics (Department)
Member
From24 Nov 2014 → Today
Projects
1 - 2 of 2
- Normalising tumour pH to bring the STING back in anti-tumour immunityFrom1 Oct 2021 → TodayFunding: FWO junior postdoctoral fellowship
- PRECISION IMMUNE-ENGINEERING OF THE TUMOR MICROENVIRONMENTFrom1 Oct 2019 → 30 Sep 2021Funding: BOF - postdoctoral mandates
Publications
11 - 20 of 28
- Water-soluble Withaferin A polymer prodrugs via a drug-functionalized RAFT CTA approach(2019)
Authors: Simon Van Herck, Benoit Louage, Raquel Pita Compostizo, Ruben De Coen, Tom Vanden Berghe, Bruno De Geest
Pages: 313 - 318 - Potent Lymphatic Translocation and Spatial Control Over Innate Immune Activation by Polymer-Lipid Amphiphile Conjugates of Small-Molecule TLR7/8 Agonists(2019)
Authors: Jana De Vrieze, Benoit Louage, Kim Deswarte, Zifu Zhong, Ruben De Coen, Simon Van Herck, Lutz Nuhn, Camilla Kaas Frich, Alexander N Zelikin, Stefan Lienenklaus, et al.
Pages: 15390 - 15395 - A synthetic, transiently thermoresponsive homopolymer with UCST behaviour within a physiologically relevant window(2019)
Authors: Zhiyue Zhang, Hui Li, Sabah Kasmi, Simon Van Herck, Kim Deswarte, Richard Hoogenboom, Lutz Nuhn, Bruno De Geest
Pages: 7866 - 7872 - The relevance of shear, sedimentation and diffusion during spin freezing, as potential first step of a continuous freeze-drying process for unit doses(2018)
Authors: Joris Lammens, Séverine Mortier, Laurens De Meyer, Brecht Vanbillemont, Pieter-Jan Van Bockstal, Simon Van Herck, Jos Corver, Ingmar Nopens, Valérie Vanhoorne, Bruno De Geest, et al.
Pages: 1 - 10 - FRET monitoring of intracellular ketal hydrolysis in synthetic nanoparticles(2018)
Authors: Lutz Nuhn, Simon Van Herck, Andreas Best, Kim Deswarte, Maria Kokkinopoulou, Ingo Lieberwirth, Kaloian Koynov, Bruno De Geest
Pages: 10760 - 10764 - Lymph-node-targeted immune activation by engineered block copolymer amphiphiles-TLR7/8 agonist conjugates(2018)
Authors: Simon Van Herck, Kim Deswarte, Lutz Nuhn, Yupeng Li, Niek Sanders, Stefan Lienenklaus, Stefaan De Koker, Sunil A David, Bruno De Geest
Pages: 14300 - 14307 - Enhanced permeability and retention-like extravasation of nanoparticles from the vasculature into tuberculosis granulomas in zebrafish and mouse models(2018)
Authors: Federico Fenaroli, Urska Repnik, Yitian Xu, Kerstin Johann, Simon Van Herck, Pradip Dey, Frode Miltzov Skjeldal, Dominik M Frei, Shahla Bagherifam, Agnese Kocere, et al.
Pages: 8646 - 8661 - Transiently thermoresponsive acetal polymers for safe and effective administration of Amphotericin B as a vaccine adjuvant(2018)
Authors: Simon Van Herck, Lien Van Hoecke, Benoit Louage, Lien Lybaert, Ruben De Coen, Sabah Kasmi, Aaron P Esser-Kahn, Sunil A David, Lutz Nuhn, Bruno De Geest
Pages: 748 - 760 - Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma(2018)
Authors: Bartosz Wiernicki, Irina Ingold, Feng Qu, Simon Van Herck, Yulia Y. Tyurina, Hülya BayU+0131r, Behnaz A. Abhari, Jose Pedro Friedmann Angeli, Eline Meul, Karen Heyninck, et al.
Pages: 3341 - 3355 - A versatile method for the selective core-crosslinking of hyaluronic acid nanogels via ketone-hydrazide chemistry : from chemical characterization to in vivo biodistribution(2018)
Authors: Francielle Pelegrin Garcia, Marlène Rippe, Mychelle VP Companhoni, Talitha Fernandes Stefanello, Benoit Louage, Simon Van Herck, Lucie Sancey, Jean-Luc Coll, Bruno De Geest, Celso Vataru Nakamura, et al.
Pages: 1754 - 1763